A systematic review and meta-analysis of mindfulness-based stress reduction for the fibromyalgia syndrome

Lauche, R; Cramer, H; Dobos, G; Langhorst, J; Schmidt, S

A systematic review and meta-analysis of mindfulness-based stress reduction for the fibromyalgia syndrome

Lauche, R

Cramer, H

Dobos, G Langhorst, J Schmidt, S

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Publication Type:: Journal Article
Citation:: Journal of Psychosomatic Research, 2013, 75 (6), pp. 500 - 510
Issue Date:: 2013-12-01

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Field	Value	Language
dc.contributor.author	Lauche, R https://orcid.org/0000-0002-4171-7935	en_US
dc.contributor.author	Cramer, H https://orcid.org/0000-0002-3640-8046	en_US
dc.contributor.author	Dobos, G	en_US
dc.contributor.author	Langhorst, J	en_US
dc.contributor.author	Schmidt, S	en_US
dc.date.available	2013-10-17	en_US
dc.date.issued	2013-12-01	en_US
dc.identifier.citation	Journal of Psychosomatic Research, 2013, 75 (6), pp. 500 - 510	en_US
dc.identifier.issn	0022-3999	en_US
dc.identifier.uri	http://hdl.handle.net/10453/116642
dc.description.abstract	Objectives: This paper presents a systematic review and meta-analysis of the effectiveness of mindfulness-based stress reduction (MBSR) for FMS. Methods: The PubMed/MEDLINE, Cochrane Library, EMBASE, PsychINFO and CAMBASE databases were screened in September 2013 to identify randomized and non-randomized controlled trials comparing MBSR to control interventions. Major outcome measures were quality of life and pain; secondary outcomes included sleep quality, fatigue, depression and safety. Standardized mean differences and 95% confidence intervals were calculated. Results: Six trials were located with a total of 674 FMS patients. Analyses revealed low quality evidence for short-term improvement of quality of life (SMD. = -0.35; 95% CI - 0.57 to - 0.12; P. = 0.002) and pain (SMD. = - 0.23; 95% CI - 0.46 to - 0.01; P. = 0.04) after MBSR, when compared to usual care; and for short-term improvement of quality of life (SMD. = - 0.32; 95% CI - 0.59 to - 0.04; P. = 0.02) and pain (SMD. = - 0.44; 95% CI - 0.73 to - 0.16; P. = 0.002) after MBSR, when compared to active control interventions. Effects were not robust against bias. No evidence was further found for secondary outcomes or long-term effects of MBSR. Safety data were not reported in any trial. Conclusions: This systematic review found that MBSR might be a useful approach for FMS patients. According to the quality of evidence only a weak recommendation for MBSR can be made at this point. Further high quality RCTs are required for a conclusive judgment of its effects. © 2013 Elsevier Inc.	en_US
dc.relation.ispartof	Journal of Psychosomatic Research	en_US
dc.relation.isbasedon	10.1016/j.jpsychores.2013.10.010	en_US
dc.subject.classification	Psychiatry	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Fibromyalgia	en_US
dc.subject.mesh	Fatigue	en_US
dc.subject.mesh	Depression	en_US
dc.subject.mesh	Stress, Psychological	en_US
dc.subject.mesh	Quality of Life	en_US
dc.subject.mesh	Outcome Assessment (Health Care)	en_US
dc.subject.mesh	Mindfulness	en_US
dc.subject.mesh	Outcome Assessment, Health Care	en_US
dc.title	A systematic review and meta-analysis of mindfulness-based stress reduction for the fibromyalgia syndrome	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	75	en_US
utslib.for	1117 Public Health and Health Services	en_US
utslib.for	1701 Psychology	en_US
utslib.for	11 Medical and Health Sciences	en_US
utslib.for	17 Psychology and Cognitive Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
utslib.copyright.status	closed_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	75	en_US

Abstract:

Objectives: This paper presents a systematic review and meta-analysis of the effectiveness of mindfulness-based stress reduction (MBSR) for FMS. Methods: The PubMed/MEDLINE, Cochrane Library, EMBASE, PsychINFO and CAMBASE databases were screened in September 2013 to identify randomized and non-randomized controlled trials comparing MBSR to control interventions. Major outcome measures were quality of life and pain; secondary outcomes included sleep quality, fatigue, depression and safety. Standardized mean differences and 95% confidence intervals were calculated. Results: Six trials were located with a total of 674 FMS patients. Analyses revealed low quality evidence for short-term improvement of quality of life (SMD. = -0.35; 95% CI - 0.57 to - 0.12; P. = 0.002) and pain (SMD. = - 0.23; 95% CI - 0.46 to - 0.01; P. = 0.04) after MBSR, when compared to usual care; and for short-term improvement of quality of life (SMD. = - 0.32; 95% CI - 0.59 to - 0.04; P. = 0.02) and pain (SMD. = - 0.44; 95% CI - 0.73 to - 0.16; P. = 0.002) after MBSR, when compared to active control interventions. Effects were not robust against bias. No evidence was further found for secondary outcomes or long-term effects of MBSR. Safety data were not reported in any trial. Conclusions: This systematic review found that MBSR might be a useful approach for FMS patients. According to the quality of evidence only a weak recommendation for MBSR can be made at this point. Further high quality RCTs are required for a conclusive judgment of its effects. © 2013 Elsevier Inc.

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http://hdl.handle.net/10453/116642