Lanthanide upconversion nanocrystals within microstructured optical fibres; A sensitive platform for biosensing and a new tool for nanocrystal characterisation
- Publication Type:
- Conference Proceeding
- Citation:
- Proceedings of SPIE - The International Society for Optical Engineering, 2012, 8351
- Issue Date:
- 2012-02-20
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We investigate a powerful new sensing platform based on upconversion luminescence in NaYF4: Yb/Er nanocrystals loaded inside a suspended-core microstructured optical fibre. The use of a NIR source enables autofluorescence from the glass to be reduced compared to using visible sources for excitation of fluorescence. We demonstrate a substantial improvement in the detection limit that can be achieved in a suspended-core fibre sensor, with detection limits as low as 660 fM achieved. This is a factor of 15× better than the best results previously reported using Quantum dots in a similar fibre. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).
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