Estimating a Dutch Value Set for the Pediatric Preference-Based CHU9D Using a Discrete Choice Experiment with Duration

Rowen, D; Mulhern, B; Stevens, K; Vermaire, JH

Estimating a Dutch Value Set for the Pediatric Preference-Based CHU9D Using a Discrete Choice Experiment with Duration

Rowen, D Mulhern, B

Stevens, K Vermaire, JH

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Publication Type:: Journal Article
Citation:: Value in Health, 2018, 21 (10), pp. 1234 - 1242
Issue Date:: 2018-10-01

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Field	Value	Language
dc.contributor.author	Rowen, D	en_US
dc.contributor.author	Mulhern, B https://orcid.org/0000-0003-3656-8063	en_US
dc.contributor.author	Stevens, K	en_US
dc.contributor.author	Vermaire, JH	en_US
dc.date.available	2020-05-25T19:07:58Z
dc.date.issued	2018-10-01	en_US
dc.identifier.citation	Value in Health, 2018, 21 (10), pp. 1234 - 1242	en_US
dc.identifier.issn	1098-3015	en_US
dc.identifier.uri	http://hdl.handle.net/10453/123048
dc.description.abstract	© 2018 ISPOR–The Professional Society for Health Economics and Outcomes Research. Objective: This article presents the development of the Dutch value set for the Child Health Utility 9D, a pediatric preference-based measure of quality of life that can be used to generate quality-adjusted life-years. Methods: A large online survey was conducted using a discrete choice experiment including a duration attribute with adult members of the Netherlands general population (N = 1276) who were representative in terms of age, gender, marital status, employment, education, and region. Respondents were asked which of two health states they prefer, where each health state was described using the nine dimensions of the Child Health Utility 9D (worried, sad, pain, tired, annoyed, school work/homework, sleep, daily routine, able to join in activities) and duration. The data were modeled using conditional logit with robust standard errors to produce utility values for every health state described by the Child Health Utility 9D. Results: The majority of the dimension level coefficients were monotonic, leading to a decrease in utility as severity increases. There was, however, evidence of some logical inconsistencies, particularly for the school work/homework dimension. The value set produced was based on the ordered model and ranges from –0.568 for the worst state to 1 for the best state. Conclusion: The valuation of the Child Health Utility 9D using online discrete choice experiment with duration with adult members of the Dutch general population was feasible and produced a valid model for use in cost utility analysis. Normative questions are raised around the valuation of pediatric preference-based measures, including the appropriate perspective for imagining hypothetical pediatric health states.	en_US
dc.relation.ispartof	Value in Health	en_US
dc.relation.isbasedon	10.1016/j.jval.2018.03.016	en_US
dc.subject.classification	Health Policy & Services	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Health Surveys	en_US
dc.subject.mesh	Choice Behavior	en_US
dc.subject.mesh	Health Status	en_US
dc.subject.mesh	Quality-Adjusted Life Years	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Child	en_US
dc.subject.mesh	Netherlands	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Young Adult	en_US
dc.subject.mesh	Child Health	en_US
dc.title	Estimating a Dutch Value Set for the Pediatric Preference-Based CHU9D Using a Discrete Choice Experiment with Duration	en_US
dc.type	Journal Article
utslib.citation.volume	10	en_US
utslib.citation.volume	21	en_US
utslib.for	1402 Applied Economics	en_US
utslib.for	1117 Public Health and Health Services	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Business
pubs.organisational-group	/University of Technology Sydney/Strength - CHERE - Centre for Health Economics Research and Evaluation
utslib.copyright.status	open_access
pubs.issue	10	en_US
pubs.publication-status	Published	en_US
pubs.volume	21	en_US

Abstract:

© 2018 ISPOR–The Professional Society for Health Economics and Outcomes Research. Objective: This article presents the development of the Dutch value set for the Child Health Utility 9D, a pediatric preference-based measure of quality of life that can be used to generate quality-adjusted life-years. Methods: A large online survey was conducted using a discrete choice experiment including a duration attribute with adult members of the Netherlands general population (N = 1276) who were representative in terms of age, gender, marital status, employment, education, and region. Respondents were asked which of two health states they prefer, where each health state was described using the nine dimensions of the Child Health Utility 9D (worried, sad, pain, tired, annoyed, school work/homework, sleep, daily routine, able to join in activities) and duration. The data were modeled using conditional logit with robust standard errors to produce utility values for every health state described by the Child Health Utility 9D. Results: The majority of the dimension level coefficients were monotonic, leading to a decrease in utility as severity increases. There was, however, evidence of some logical inconsistencies, particularly for the school work/homework dimension. The value set produced was based on the ordered model and ranges from –0.568 for the worst state to 1 for the best state. Conclusion: The valuation of the Child Health Utility 9D using online discrete choice experiment with duration with adult members of the Dutch general population was feasible and produced a valid model for use in cost utility analysis. Normative questions are raised around the valuation of pediatric preference-based measures, including the appropriate perspective for imagining hypothetical pediatric health states.

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http://hdl.handle.net/10453/123048