Silica shell-assisted synthetic route for mono-disperse persistent nanophosphors with enhanced in vivo recharged near-infrared persistent luminescence

Zou, R; Huang, J; Shi, J; Huang, L; Zhang, X; Wong, KL; Zhang, H; Jin, D; Wang, J; Su, Q

Silica shell-assisted synthetic route for mono-disperse persistent nanophosphors with enhanced in vivo recharged near-infrared persistent luminescence

Zou, R Huang, J Shi, J Huang, L Zhang, X Wong, KL Zhang, H Jin, D

Wang, J Su, Q

Permalink

Publication Type:: Journal Article
Citation:: Nano Research, 2017, 10 (6), pp. 2070 - 2082
Issue Date:: 2017-06-01

Closed Access

	Filename	Description	Size
	10.1007%2Fs12274-016-1396-z.pdf	Published Version	3.27 MB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Zou, R	en_US
dc.contributor.author	Huang, J	en_US
dc.contributor.author	Shi, J	en_US
dc.contributor.author	Huang, L	en_US
dc.contributor.author	Zhang, X	en_US
dc.contributor.author	Wong, KL	en_US
dc.contributor.author	Zhang, H	en_US
dc.contributor.author	Jin, D https://orcid.org/0000-0003-1046-2666	en_US
dc.contributor.author	Wang, J	en_US
dc.contributor.author	Su, Q	en_US
dc.date.issued	2017-06-01	en_US
dc.identifier.citation	Nano Research, 2017, 10 (6), pp. 2070 - 2082	en_US
dc.identifier.issn	1998-0124	en_US
dc.identifier.uri	http://hdl.handle.net/10453/124770
dc.description.abstract	© 2016, Tsinghua University Press and Springer-Verlag Berlin Heidelberg. Near-infrared (NIR) persistent-luminescence nanoparticles have emerged as a new class of background-free contrast agents that are promising for in vivo imaging. The next key roadblock is to establish a robust and controllable method for synthesizing monodisperse nanoparticles with high luminescence brightness and long persistent duration. Herein, we report a synthesis strategy involving the coating/etching of the SiO2 shell to obtain a new class of small NIR highly persistent luminescent ZnGa2O4:Cr3+,Sn4+ (ZGOCS) nanoparticles. The optimized ZGOCS nanoparticles have an excellent size distribution of ~15 nm without any agglomeration and an NIR persistent luminescence that is enhanced by a factor of 13.5, owing to the key role of the SiO2 shell in preventing nanoparticle agglomeration after annealing. The ZGOCS nanoparticles have a signal-to-noise ratio ~3 times higher than that of previously reported ZnGa2O4:Cr3+ (ZGC-1) nanoparticles as an NIR persistent-luminescence probe for in vivo bioimaging. Moreover, the persistent-luminescence signal from the ZGOCS nanoparticles can be repeatedly re-charged in situ with external excitation by a white lightemitting diode; thus, the nanoparticles are suitable for long-term in vivo imaging applications. Our study suggests an improved strategy for fabricating novel high-performance optical nanoparticles with good biocompatibility.	en_US
dc.relation.ispartof	Nano Research	en_US
dc.relation.isbasedon	10.1007/s12274-016-1396-z	en_US
dc.subject.classification	Nanoscience & Nanotechnology	en_US
dc.title	Silica shell-assisted synthetic route for mono-disperse persistent nanophosphors with enhanced in vivo recharged near-infrared persistent luminescence	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	10	en_US
utslib.for	1007 Nanotechnology	en_US
utslib.for	MD Multidisciplinary	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	closed_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	10	en_US

Abstract:

© 2016, Tsinghua University Press and Springer-Verlag Berlin Heidelberg. Near-infrared (NIR) persistent-luminescence nanoparticles have emerged as a new class of background-free contrast agents that are promising for in vivo imaging. The next key roadblock is to establish a robust and controllable method for synthesizing monodisperse nanoparticles with high luminescence brightness and long persistent duration. Herein, we report a synthesis strategy involving the coating/etching of the SiO2 shell to obtain a new class of small NIR highly persistent luminescent ZnGa2O4:Cr3+,Sn4+ (ZGOCS) nanoparticles. The optimized ZGOCS nanoparticles have an excellent size distribution of ~15 nm without any agglomeration and an NIR persistent luminescence that is enhanced by a factor of 13.5, owing to the key role of the SiO2 shell in preventing nanoparticle agglomeration after annealing. The ZGOCS nanoparticles have a signal-to-noise ratio ~3 times higher than that of previously reported ZnGa2O4:Cr3+ (ZGC-1) nanoparticles as an NIR persistent-luminescence probe for in vivo bioimaging. Moreover, the persistent-luminescence signal from the ZGOCS nanoparticles can be repeatedly re-charged in situ with external excitation by a white lightemitting diode; thus, the nanoparticles are suitable for long-term in vivo imaging applications. Our study suggests an improved strategy for fabricating novel high-performance optical nanoparticles with good biocompatibility.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/124770