The effect of high-intensity aerobic interval training on markers of systemic inflammation in sedentary populations

Allen, NG; Higham, SM; Mendham, AE; Kastelein, TE; Larsen, PS; Duffield, R

The effect of high-intensity aerobic interval training on markers of systemic inflammation in sedentary populations

Allen, NG Higham, SM

Mendham, AE Kastelein, TE Larsen, PS Duffield, R

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Publication Type:: Journal Article
Citation:: European Journal of Applied Physiology, 2017, 117 (6), pp. 1249 - 1256
Issue Date:: 2017-06-01

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Field	Value	Language
dc.contributor.author	Allen, NG	en_US
dc.contributor.author	Higham, SM https://orcid.org/0000-0003-1420-8825	en_US
dc.contributor.author	Mendham, AE	en_US
dc.contributor.author	Kastelein, TE	en_US
dc.contributor.author	Larsen, PS	en_US
dc.contributor.author	Duffield, R https://orcid.org/0000-0002-5641-1314	en_US
dc.date.available	2017-04-10	en_US
dc.date.issued	2017-06-01	en_US
dc.identifier.citation	European Journal of Applied Physiology, 2017, 117 (6), pp. 1249 - 1256	en_US
dc.identifier.issn	1439-6319	en_US
dc.identifier.uri	http://hdl.handle.net/10453/125081
dc.description.abstract	© 2017, Springer-Verlag Berlin Heidelberg. Purpose: This study examined the effects of high-intensity interval training (HIIT; 30 s sprint, 4–5 min passive recovery) and prolonged intermittent sprint training (PIST; 10 s sprint, 2–3 min moderate exercise) on the systemic inflammatory markers C-reactive protein (CRP) and tumor necrosis factor-α (TNF-α), aerobic capacity, and anthropometry in a middle-aged, sedentary population. Methods: Fifty-five sedentary adults (age 49.2 ± 6.1 years) were randomised into HIIT (n = 20), PIST (n = 21), or a sedentary control group (CTRL n = 14). HIIT and PIST performed three training sessions per week for 9 weeks on a cycle ergometer, matched for total high-intensity time, while CTRL continued normal sedentary behaviours. Pre- and post-intervention testing involved measures of anthropometry, peak oxygen consumption (VO2peak), and venous blood collection for analyses of CRP and TNF-α. Results: HIIT and PIST increased VO2peak compared to CTRL (+3.66 ± 2.23 and 3.74 ± 2.62 mL kg min−1). A group × time interaction (p = 0.042) and main effect of time (p = 0.026) were evident for waist girth, with only HIIT showing a significant reduction compared to CTRL (−2.1 ± 2.8 cm). TNF-α and CRP showed no group × time interaction or time effect (p > 0.05). Conclusions: In sedentary individuals, 9 weeks of HIIT or PIST were effective to improve aerobic capacity; however, only HIIT significantly reduced waist girth and WHR compared to CTRL. Markers of systemic inflammation remained unchanged across all groups. Accordingly, for inflammation and VO2peak, the distribution of sprints and the active or passive recovery periods are inconsequential provided that total duration of high-intensity efforts is similar.	en_US
dc.relation.ispartof	European Journal of Applied Physiology	en_US
dc.relation.isbasedon	10.1007/s00421-017-3613-1	en_US
dc.subject.classification	Sport Sciences	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Tumor Necrosis Factor-alpha	en_US
dc.subject.mesh	C-Reactive Protein	en_US
dc.subject.mesh	Oxygen Consumption	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Waist Circumference	en_US
dc.subject.mesh	Sedentary Lifestyle	en_US
dc.subject.mesh	High-Intensity Interval Training	en_US
dc.subject.mesh	Sedentary Behavior	en_US
dc.title	The effect of high-intensity aerobic interval training on markers of systemic inflammation in sedentary populations	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	117	en_US
utslib.for	1106 Human Movement and Sports Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Public Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Sports and Exercise Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney/Students
utslib.copyright.status	open_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	117	en_US

Abstract:

© 2017, Springer-Verlag Berlin Heidelberg. Purpose: This study examined the effects of high-intensity interval training (HIIT; 30 s sprint, 4–5 min passive recovery) and prolonged intermittent sprint training (PIST; 10 s sprint, 2–3 min moderate exercise) on the systemic inflammatory markers C-reactive protein (CRP) and tumor necrosis factor-α (TNF-α), aerobic capacity, and anthropometry in a middle-aged, sedentary population. Methods: Fifty-five sedentary adults (age 49.2 ± 6.1 years) were randomised into HIIT (n = 20), PIST (n = 21), or a sedentary control group (CTRL n = 14). HIIT and PIST performed three training sessions per week for 9 weeks on a cycle ergometer, matched for total high-intensity time, while CTRL continued normal sedentary behaviours. Pre- and post-intervention testing involved measures of anthropometry, peak oxygen consumption (VO2peak), and venous blood collection for analyses of CRP and TNF-α. Results: HIIT and PIST increased VO2peak compared to CTRL (+3.66 ± 2.23 and 3.74 ± 2.62 mL kg min−1). A group × time interaction (p = 0.042) and main effect of time (p = 0.026) were evident for waist girth, with only HIIT showing a significant reduction compared to CTRL (−2.1 ± 2.8 cm). TNF-α and CRP showed no group × time interaction or time effect (p > 0.05). Conclusions: In sedentary individuals, 9 weeks of HIIT or PIST were effective to improve aerobic capacity; however, only HIIT significantly reduced waist girth and WHR compared to CTRL. Markers of systemic inflammation remained unchanged across all groups. Accordingly, for inflammation and VO2peak, the distribution of sprints and the active or passive recovery periods are inconsequential provided that total duration of high-intensity efforts is similar.

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http://hdl.handle.net/10453/125081