Visualization and analysis of 3D microscopic images

Long, F; Zhou, J; Peng, H

Visualization and analysis of 3D microscopic images

Long, F Zhou, J

Peng, H

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Publication Type:: Journal Article
Citation:: PLoS Computational Biology, 2012, 8 (6)
Issue Date:: 2012-06-01

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Field	Value	Language
dc.contributor.author	Long, F	en_US
dc.contributor.author	Zhou, J https://orcid.org/0000-0001-6034-644X	en_US
dc.contributor.author	Peng, H	en_US
dc.date.issued	2012-06-01	en_US
dc.identifier.citation	PLoS Computational Biology, 2012, 8 (6)	en_US
dc.identifier.issn	1553-734X	en_US
dc.identifier.uri	http://hdl.handle.net/10453/131813
dc.description.abstract	In a wide range of biological studies, it is highly desirable to visualize and analyze three-dimensional (3D) microscopic images. In this primer, we first introduce several major methods for visualizing typical 3D images and related multi-scale, multi-time-point, multi-color data sets. Then, we discuss three key categories of image analysis tasks, namely segmentation, registration, and annotation. We demonstrate how to pipeline these visualization and analysis modules using examples of profiling the single-cell gene-expression of C. elegans and constructing a map of stereotyped neurite tracts in a fruit fly brain. © 2012 Long et al.	en_US
dc.relation.ispartof	PLoS Computational Biology	en_US
dc.relation.isbasedon	10.1371/journal.pcbi.1002519	en_US
dc.subject.classification	Bioinformatics	en_US
dc.subject.mesh	Brain	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Drosophila melanogaster	en_US
dc.subject.mesh	Caenorhabditis elegans	en_US
dc.subject.mesh	Imaging, Three-Dimensional	en_US
dc.subject.mesh	Microscopy	en_US
dc.subject.mesh	Gene Expression Profiling	en_US
dc.subject.mesh	Computational Biology	en_US
dc.subject.mesh	Computer Simulation	en_US
dc.title	Visualization and analysis of 3D microscopic images	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	8	en_US
utslib.for	01 Mathematical Sciences	en_US
utslib.for	06 Biological Sciences	en_US
utslib.for	08 Information and Computing Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
utslib.copyright.status	open_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	8	en_US

Abstract:

In a wide range of biological studies, it is highly desirable to visualize and analyze three-dimensional (3D) microscopic images. In this primer, we first introduce several major methods for visualizing typical 3D images and related multi-scale, multi-time-point, multi-color data sets. Then, we discuss three key categories of image analysis tasks, namely segmentation, registration, and annotation. We demonstrate how to pipeline these visualization and analysis modules using examples of profiling the single-cell gene-expression of C. elegans and constructing a map of stereotyped neurite tracts in a fruit fly brain. © 2012 Long et al.

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http://hdl.handle.net/10453/131813