Phytosterol biosynthesis and production by diatoms (Bacillariophyceae)
- Publication Type:
- Journal Article
- Citation:
- Phytochemistry, 2019, 163 pp. 46 - 57
- Issue Date:
- 2019-07-01
Closed Access
Filename | Description | Size | |||
---|---|---|---|---|---|
1-s2.0-S0031942218303698-main.pdf | Published Version | 1.53 MB |
Copyright Clearance Process
- Recently Added
- In Progress
- Closed Access
This item is closed access and not available.
© 2019 Elsevier Ltd Diatoms are abundant unicellular marine photosynthetic algae that have genetically diversified their physiology and metabolism while adapting to numerous environments. The metabolic repertoire of diatoms presents opportunities to characterise the biosynthesis and production of new and potentially valuable microalgal compounds, including sterols. Sterols of plant origin, known as phytosterols, have been studied for health benefits including demonstrated cholesterol-lowering properties. In this review we summarise sterol diversity, the unique metabolic features of sterol biosynthesis in diatoms, and prospects for the extraction of diatom phytosterols in comparison to existing sources. We also review biotechnological efforts to manipulate diatom biosynthesis, including culture conditions and avenues for the rational engineering of metabolism and cellular regulation.
Please use this identifier to cite or link to this item: