Enabling respiratory control after severe chronic tetraplegia: an exploratory case study.

Gad, P; Kreydin, E; Zhong, H; Edgerton, VR

Enabling respiratory control after severe chronic tetraplegia: an exploratory case study.

Gad, P Kreydin, E Zhong, H Edgerton, VR

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Publisher:: American Physiological Society
Publication Type:: Journal Article
Citation:: Journal of neurophysiology, 2020, 124, (3), pp. 774-780
Issue Date:: 2020-09

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Field	Value	Language
dc.contributor.author	Gad, P
dc.contributor.author	Kreydin, E
dc.contributor.author	Zhong, H
dc.contributor.author	Edgerton, VR
dc.date.accessioned	2021-02-24T00:05:24Z
dc.date.available	2021-02-24T00:05:24Z
dc.date.issued	2020-09
dc.identifier.citation	Journal of neurophysiology, 2020, 124, (3), pp. 774-780
dc.identifier.issn	0022-3077
dc.identifier.issn	1522-1598
dc.identifier.uri	http://hdl.handle.net/10453/146372
dc.description.abstract	Respiratory dysfunction is one of the most debilitating effects of spinal cord injury (SCI) impacting the quality of life of patients and caregivers. In addition, breathing difficulties impact the rehabilitation routine a patient may potentially undergo. Transcutaneous electrical spinal cord neuromodulation (TESCoN) is a novel approach to reactivate and retrain spinal circuits after paralysis. We demonstrate that acute and chronic TESCoN therapy over the cervical spinal cord positively impacts the breathing and coughing ability in a patient with chronic tetraplegia. ln addition, we show that the improved breathing and coughing ability are not only observed in the presence of TESCoN but persisted for a few days after TESCoN was stopped.<b>NEW & NOTEWORTHY</b> Noninvasive spinal neuromodulation improves breathing and coughing in a patient with severe and complete tetraplegia.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	American Physiological Society
dc.relation.ispartof	Journal of neurophysiology
dc.relation.isbasedon	10.1152/jn.00320.2020
dc.rights	info:eu-repo/semantics/embargoedAccess
dc.subject	11 Medical and Health Sciences, 17 Psychology and Cognitive Sciences
dc.subject.classification	Neurology & Neurosurgery
dc.title	Enabling respiratory control after severe chronic tetraplegia: an exploratory case study.
dc.type	Journal Article
utslib.citation.volume	124
utslib.location.activity	United States
utslib.for	11 Medical and Health Sciences
utslib.for	17 Psychology and Cognitive Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	open_access	*
utslib.copyright.embargo	2021-09-01T00:00:00+1000Z
dc.date.updated	2021-02-24T00:05:21Z
pubs.issue	3
pubs.publication-status	Published
pubs.volume	124
utslib.citation.issue	3

Abstract:

Respiratory dysfunction is one of the most debilitating effects of spinal cord injury (SCI) impacting the quality of life of patients and caregivers. In addition, breathing difficulties impact the rehabilitation routine a patient may potentially undergo. Transcutaneous electrical spinal cord neuromodulation (TESCoN) is a novel approach to reactivate and retrain spinal circuits after paralysis. We demonstrate that acute and chronic TESCoN therapy over the cervical spinal cord positively impacts the breathing and coughing ability in a patient with chronic tetraplegia. ln addition, we show that the improved breathing and coughing ability are not only observed in the presence of TESCoN but persisted for a few days after TESCoN was stopped.NEW & NOTEWORTHY Noninvasive spinal neuromodulation improves breathing and coughing in a patient with severe and complete tetraplegia.

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http://hdl.handle.net/10453/146372