Preventing depression in older people with multimorbidity: 24-month follow-up of a trial of internet-delivered cognitive behaviour therapy.

Read, JR; Sharpe, L; Burton, AL; Areán, PA; Raue, PJ; McDonald, S; Titov, N; Gandy, M; Dear, BF

Preventing depression in older people with multimorbidity: 24-month follow-up of a trial of internet-delivered cognitive behaviour therapy.

Read, JR Sharpe, L Burton, AL Areán, PA Raue, PJ McDonald, S

Titov, N Gandy, M Dear, BF

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Publisher:: British Geriatrics Society
Publication Type:: Journal Article
Citation:: Age and Ageing, 2021, 50, (6), pp. 2254-2258
Issue Date:: 2021-11

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Field	Value	Language
dc.contributor.author	Read, JR
dc.contributor.author	Sharpe, L
dc.contributor.author	Burton, AL
dc.contributor.author	Areán, PA
dc.contributor.author	Raue, PJ
dc.contributor.author	McDonald, S https://orcid.org/0000-0001-8872-4852
dc.contributor.author	Titov, N
dc.contributor.author	Gandy, M
dc.contributor.author	Dear, BF
dc.date.accessioned	2021-12-13T05:40:07Z
dc.date.available	2021-12-13T05:40:07Z
dc.date.issued	2021-11
dc.identifier.citation	Age and Ageing, 2021, 50, (6), pp. 2254-2258
dc.identifier.issn	0002-0729
dc.identifier.issn	1468-2834
dc.identifier.uri	http://hdl.handle.net/10453/152291
dc.description.abstract	Background older people coping with the impacts of living with multimorbidity are at increased risk of developing a depressive disorder. Objective this article reports the 24-month results of a randomised controlled trial of an internet-delivered cognitive behaviour therapy, which aimed to test whether depressive disorders could be prevented in this population. Participants community-based participants aged 65 years and over, who had two or more chronic physical health conditions and were assessed as having no current depressive disorder. Methods in total, 302 participants were randomised to an 8-week, five-lesson, internet-delivered intervention program (n = 150) or treatment as usual (TAU, n = 152). The primary outcomes were cases of depressive disorder, assessed post-intervention and at 3-month intervals throughout the trial, and depressive symptoms, assessed at pre-intervention, post-intervention, 6, 12 and 24 months following the intervention. Results there were significantly fewer cases of depressive disorder in the intervention group (n = 23, 15%) compared with the TAU group (n = 41, 27%) during the 24 months after the intervention (χ2(1, N = 302) = 6.13, P = 0.013, odds ratio = 0.490 [95% confidence interval: 0.277, 0.867]), representing a 44% reduction in cases of depressive disorder. No differences were found on depressive symptoms at 24-month follow-up. Internet-delivered cognitive behaviour therapy had high engagement and acceptability. Conclusions the results provide support that depressive disorders can be prevented in older people with multimorbidity through participation in internet-delivered cognitive behaviour therapy. With access to internet-delivered interventions in clinical care settings increasing, this has implications for older patient care where multimorbidity is extremely common.
dc.format	Print
dc.language	eng
dc.publisher	British Geriatrics Society
dc.relation.ispartof	Age and Ageing
dc.relation.isbasedon	10.1093/ageing/afab145
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1103 Clinical Sciences, 1117 Public Health and Health Services, 1701 Psychology
dc.subject.classification	Geriatrics
dc.subject.mesh	Aged
dc.subject.mesh	Cognitive Behavioral Therapy
dc.subject.mesh	Depression
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Humans
dc.subject.mesh	Internet
dc.subject.mesh	Multimorbidity
dc.subject.mesh	Treatment Outcome
dc.subject.mesh	Humans
dc.subject.mesh	Treatment Outcome
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Depression
dc.subject.mesh	Internet
dc.subject.mesh	Aged
dc.subject.mesh	Multimorbidity
dc.subject.mesh	Cognitive Behavioral Therapy
dc.subject.mesh	Aged
dc.subject.mesh	Cognitive Behavioral Therapy
dc.subject.mesh	Depression
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Humans
dc.subject.mesh	Internet
dc.subject.mesh	Multimorbidity
dc.subject.mesh	Treatment Outcome
dc.title	Preventing depression in older people with multimorbidity: 24-month follow-up of a trial of internet-delivered cognitive behaviour therapy.
dc.type	Journal Article
utslib.citation.volume	50
utslib.location.activity	England
utslib.for	1103 Clinical Sciences
utslib.for	1117 Public Health and Health Services
utslib.for	1701 Psychology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Clinical Psychology
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2021-12-13T05:40:06Z
pubs.issue	6
pubs.publication-status	Published
pubs.volume	50
utslib.citation.issue	6

Abstract:

Background older people coping with the impacts of living with multimorbidity are at increased risk of developing a depressive disorder. Objective this article reports the 24-month results of a randomised controlled trial of an internet-delivered cognitive behaviour therapy, which aimed to test whether depressive disorders could be prevented in this population. Participants community-based participants aged 65 years and over, who had two or more chronic physical health conditions and were assessed as having no current depressive disorder. Methods in total, 302 participants were randomised to an 8-week, five-lesson, internet-delivered intervention program (n = 150) or treatment as usual (TAU, n = 152). The primary outcomes were cases of depressive disorder, assessed post-intervention and at 3-month intervals throughout the trial, and depressive symptoms, assessed at pre-intervention, post-intervention, 6, 12 and 24 months following the intervention. Results there were significantly fewer cases of depressive disorder in the intervention group (n = 23, 15%) compared with the TAU group (n = 41, 27%) during the 24 months after the intervention (χ2(1, N = 302) = 6.13, P = 0.013, odds ratio = 0.490 [95% confidence interval: 0.277, 0.867]), representing a 44% reduction in cases of depressive disorder. No differences were found on depressive symptoms at 24-month follow-up. Internet-delivered cognitive behaviour therapy had high engagement and acceptability. Conclusions the results provide support that depressive disorders can be prevented in older people with multimorbidity through participation in internet-delivered cognitive behaviour therapy. With access to internet-delivered interventions in clinical care settings increasing, this has implications for older patient care where multimorbidity is extremely common.

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http://hdl.handle.net/10453/152291