Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

Ditz, B; Boekhoudt, JG; Aliee, H; Theis, FJ; Nawijn, M; Brandsma, C-A; Hiemstra, PS; Timens, W; Tew, GW; Grimbaldeston, MA; Neighbors, M; Guryev, V; van den Berge, M; Faiz, A

Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

Ditz, B Boekhoudt, JG Aliee, H Theis, FJ Nawijn, M Brandsma, C-A Hiemstra, PS Timens, W Tew, GW Grimbaldeston, MA Neighbors, M Guryev, V van den Berge, M Faiz, A

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Publisher:: European Respiratory Society (ERS)
Publication Type:: Journal Article
Citation:: ERJ Open Res, 2021, 7, (2), pp. 00104-02021
Issue Date:: 2021-04

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Field	Value	Language
dc.contributor.author	Ditz, B
dc.contributor.author	Boekhoudt, JG
dc.contributor.author	Aliee, H
dc.contributor.author	Theis, FJ
dc.contributor.author	Nawijn, M
dc.contributor.author	Brandsma, C-A
dc.contributor.author	Hiemstra, PS
dc.contributor.author	Timens, W
dc.contributor.author	Tew, GW
dc.contributor.author	Grimbaldeston, MA
dc.contributor.author	Neighbors, M
dc.contributor.author	Guryev, V
dc.contributor.author	van den Berge, M
dc.contributor.author	Faiz, A https://orcid.org/0000-0003-1740-3538
dc.date.accessioned	2022-01-27T23:15:24Z
dc.date.available	2021-03-02
dc.date.available	2022-01-27T23:15:24Z
dc.date.issued	2021-04
dc.identifier.citation	ERJ Open Res, 2021, 7, (2), pp. 00104-02021
dc.identifier.issn	2312-0541
dc.identifier.issn	2312-0541
dc.identifier.uri	http://hdl.handle.net/10453/153681
dc.description.abstract	More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s.
dc.format	Electronic-eCollection
dc.language	eng
dc.publisher	European Respiratory Society (ERS)
dc.relation.ispartof	ERJ Open Res
dc.relation.isbasedon	10.1183/23120541.00104-2021
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?
dc.type	Journal Article
utslib.citation.volume	7
utslib.location.activity	England
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	open_access	*
dc.date.updated	2022-01-27T23:15:22Z
pubs.issue	2
pubs.publication-status	Published online
pubs.volume	7
utslib.citation.issue	2

Abstract:

More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/153681