Toxicity assessment of New Zealand and Pacific dinoflagellates Ostreopsis and Gambierdiscus (Dinophyceae) extracts using bioassays

Argyle, PA; Harwood, DT; Rhodes, LL; Champeau, O; Tremblay, LA

Toxicity assessment of New Zealand and Pacific dinoflagellates Ostreopsis and Gambierdiscus (Dinophyceae) extracts using bioassays

Argyle, PA Harwood, DT Rhodes, LL Champeau, O Tremblay, LA

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Publisher:: Informa UK Limited
Publication Type:: Journal Article
Citation:: New Zealand Journal of Marine and Freshwater Research, 2016, 50, (3), pp. 444-456
Issue Date:: 2016-07-02

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Field	Value	Language
dc.contributor.author	Argyle, PA
dc.contributor.author	Harwood, DT
dc.contributor.author	Rhodes, LL
dc.contributor.author	Champeau, O
dc.contributor.author	Tremblay, LA
dc.date.accessioned	2022-08-20T21:08:57Z
dc.date.available	2022-08-20T21:08:57Z
dc.date.issued	2016-07-02
dc.identifier.citation	New Zealand Journal of Marine and Freshwater Research, 2016, 50, (3), pp. 444-456
dc.identifier.issn	0028-8330
dc.identifier.issn	1175-8805
dc.identifier.uri	http://hdl.handle.net/10453/160580
dc.description.abstract	The dinoflagellate genus Ostreopsis produces palytoxin-like compounds (PLTXs) and the genus Gambierdiscus produces ciguatoxins (CTXs) and maitotoxin (MTX). Human illness has been recorded following the consumption of CTX-contaminated finfish. Their effects on the flora and fauna in the environment are largely unexplored. Toxin profiles of extracts of Ostreopsis and Gambierdiscus isolates from the Pacific region were characterised using liquid chromatography tandem mass spectrometry. Sea urchin (Evechinus chloriticus) fertilisation was unaffected by any algal extracts, but extracts containing maitotoxin-3 (MTX-3, but not MTX or CTXs), or with high concentrations of PLTXs, were toxic to urchin larval development. Gambierdiscus extracts containing CTXs elicited toxic responses in zebrafish (Danio rerio) embryo toxicity assays; extracts containing only MTX-3 elicited a limited response. Ostreopsis extracts containing PLTXs caused no response. The results demonstrate potential impacts of toxic dinoflagellates on larval organisms and the potential of embryonic assays as toxicity screening tools.
dc.language	en
dc.publisher	Informa UK Limited
dc.relation.ispartof	New Zealand Journal of Marine and Freshwater Research
dc.relation.isbasedon	10.1080/00288330.2016.1159581
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	04 Earth Sciences, 05 Environmental Sciences, 06 Biological Sciences
dc.subject.classification	Marine Biology & Hydrobiology
dc.title	Toxicity assessment of New Zealand and Pacific dinoflagellates Ostreopsis and Gambierdiscus (Dinophyceae) extracts using bioassays
dc.type	Journal Article
utslib.citation.volume	50
utslib.for	04 Earth Sciences
utslib.for	05 Environmental Sciences
utslib.for	06 Biological Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - C3 - Climate Change Cluster
utslib.copyright.status	closed_access	*
dc.date.updated	2022-08-20T21:08:55Z
pubs.issue	3
pubs.publication-status	Published
pubs.volume	50
utslib.citation.issue	3

Abstract:

The dinoflagellate genus Ostreopsis produces palytoxin-like compounds (PLTXs) and the genus Gambierdiscus produces ciguatoxins (CTXs) and maitotoxin (MTX). Human illness has been recorded following the consumption of CTX-contaminated finfish. Their effects on the flora and fauna in the environment are largely unexplored. Toxin profiles of extracts of Ostreopsis and Gambierdiscus isolates from the Pacific region were characterised using liquid chromatography tandem mass spectrometry. Sea urchin (Evechinus chloriticus) fertilisation was unaffected by any algal extracts, but extracts containing maitotoxin-3 (MTX-3, but not MTX or CTXs), or with high concentrations of PLTXs, were toxic to urchin larval development. Gambierdiscus extracts containing CTXs elicited toxic responses in zebrafish (Danio rerio) embryo toxicity assays; extracts containing only MTX-3 elicited a limited response. Ostreopsis extracts containing PLTXs caused no response. The results demonstrate potential impacts of toxic dinoflagellates on larval organisms and the potential of embryonic assays as toxicity screening tools.

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http://hdl.handle.net/10453/160580