A guide to the design of magnetic particle imaging tracers for biomedical applications.
- Publisher:
- Royal Society of Chemistry (RSC)
- Publication Type:
- Journal Article
- Citation:
- Nanoscale, 2022, 14, (38), pp. 13890-13914
- Issue Date:
- 2022-10-06
Closed Access
Filename | Description | Size | |||
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d2nr01897g.pdf | Published version | 5.75 MB | Adobe PDF |
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Full metadata record
Field | Value | Language |
---|---|---|
dc.contributor.author | Duong, HTK | |
dc.contributor.author | Abdibastami, A | |
dc.contributor.author |
Gloag, L |
|
dc.contributor.author | Barrera, L | |
dc.contributor.author | Gooding, JJ | |
dc.contributor.author | Tilley, RD | |
dc.date.accessioned | 2023-04-03T22:19:31Z | |
dc.date.available | 2023-04-03T22:19:31Z | |
dc.date.issued | 2022-10-06 | |
dc.identifier.citation | Nanoscale, 2022, 14, (38), pp. 13890-13914 | |
dc.identifier.issn | 2040-3364 | |
dc.identifier.issn | 2040-3372 | |
dc.identifier.uri | http://hdl.handle.net/10453/169086 | |
dc.description.abstract | Magnetic Particle Imaging (MPI) is a novel and emerging non-invasive technique that promises to deliver high quality images, no radiation, high depth penetration and nearly no background from tissues. Signal intensity and spatial resolution in MPI are heavily dependent on the properties of tracers. Hence the selection of these nanoparticles for various applications in MPI must be carefully considered to achieve optimum results. In this review, we will provide an overview of the principle of MPI and the key criteria that are required for tracers in order to generate the best signals. Nanoparticle materials such as magnetite, metal ferrites, maghemite, zero valent iron@iron oxide core@shell, iron carbide and iron-cobalt alloy nanoparticles will be discussed as well as their synthetic pathways. Since surface modifications play an important role in enabling the use of these tracers for biomedical applications, coating options including the transfer from organic to inorganic media will also be discussed. Finally, we will discuss different biomedical applications and provide our insights into the most suitable tracer for each of these applications. | |
dc.format | Electronic | |
dc.language | eng | |
dc.publisher | Royal Society of Chemistry (RSC) | |
dc.relation.ispartof | Nanoscale | |
dc.relation.isbasedon | 10.1039/d2nr01897g | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | 02 Physical Sciences, 03 Chemical Sciences, 10 Technology | |
dc.subject.classification | Nanoscience & Nanotechnology | |
dc.subject.mesh | Alloys | |
dc.subject.mesh | Cobalt | |
dc.subject.mesh | Ferric Compounds | |
dc.subject.mesh | Ferrosoferric Oxide | |
dc.subject.mesh | Iron | |
dc.subject.mesh | Magnetic Phenomena | |
dc.subject.mesh | Magnetite Nanoparticles | |
dc.subject.mesh | Cobalt | |
dc.subject.mesh | Iron | |
dc.subject.mesh | Ferric Compounds | |
dc.subject.mesh | Alloys | |
dc.subject.mesh | Ferrosoferric Oxide | |
dc.subject.mesh | Magnetite Nanoparticles | |
dc.subject.mesh | Magnetic Phenomena | |
dc.subject.mesh | Alloys | |
dc.subject.mesh | Cobalt | |
dc.subject.mesh | Ferric Compounds | |
dc.subject.mesh | Ferrosoferric Oxide | |
dc.subject.mesh | Iron | |
dc.subject.mesh | Magnetic Phenomena | |
dc.subject.mesh | Magnetite Nanoparticles | |
dc.title | A guide to the design of magnetic particle imaging tracers for biomedical applications. | |
dc.type | Journal Article | |
utslib.citation.volume | 14 | |
utslib.location.activity | England | |
utslib.for | 02 Physical Sciences | |
utslib.for | 03 Chemical Sciences | |
utslib.for | 10 Technology | |
pubs.organisational-group | /University of Technology Sydney | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Science | |
pubs.organisational-group | /University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences | |
utslib.copyright.status | closed_access | * |
dc.date.updated | 2023-04-03T22:19:27Z | |
pubs.issue | 38 | |
pubs.publication-status | Published online | |
pubs.volume | 14 | |
utslib.citation.issue | 38 |
Abstract:
Magnetic Particle Imaging (MPI) is a novel and emerging non-invasive technique that promises to deliver high quality images, no radiation, high depth penetration and nearly no background from tissues. Signal intensity and spatial resolution in MPI are heavily dependent on the properties of tracers. Hence the selection of these nanoparticles for various applications in MPI must be carefully considered to achieve optimum results. In this review, we will provide an overview of the principle of MPI and the key criteria that are required for tracers in order to generate the best signals. Nanoparticle materials such as magnetite, metal ferrites, maghemite, zero valent iron@iron oxide core@shell, iron carbide and iron-cobalt alloy nanoparticles will be discussed as well as their synthetic pathways. Since surface modifications play an important role in enabling the use of these tracers for biomedical applications, coating options including the transfer from organic to inorganic media will also be discussed. Finally, we will discuss different biomedical applications and provide our insights into the most suitable tracer for each of these applications.
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