Evaluation of an enhanced service for medication review with follow up in Swiss community pharmacies: Pre-post study protocol

Amador-Fernández, N; Escaith, M; Simi, E; Quintana-Bárcena, P; Berger, J

Evaluation of an enhanced service for medication review with follow up in Swiss community pharmacies: Pre-post study protocol

Amador-Fernández, N Escaith, M Simi, E Quintana-Bárcena, P Berger, J

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Publisher:: Public Library of Science (PLoS)
Publication Type:: Journal Article
Citation:: PLOS ONE, 18, (10), pp. e0292037-e0292037

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Field	Value	Language
dc.contributor.author	Amador-Fernández, N
dc.contributor.author	Escaith, M
dc.contributor.author	Simi, E
dc.contributor.author	Quintana-Bárcena, P
dc.contributor.author	Berger, J
dc.contributor.editor	Köpke, S
dc.date.accessioned	2023-10-19T05:54:25Z
dc.date.available	2023-10-19T05:54:25Z
dc.identifier.citation	PLOS ONE, 18, (10), pp. e0292037-e0292037
dc.identifier.issn	1932-6203
dc.identifier.uri	http://hdl.handle.net/10453/172809
dc.description.abstract	<jats:sec id="sec001"> <jats:title>Background</jats:title> <jats:p>In Switzerland, 20,000 people are hospitalized each year as result of drug related problems (DRPs). The sources of DRPs can be related to patients’ behavior (i.e., wrong administration) or to health processes (i.e., drug-drug interaction). No community pharmacy (CP) service focus on DRPs related to patients’ behavior is currently recognized or remunerated in Switzerland. A medication review with follow up (MRF) has been developed to evaluate prescription and non-prescription medication.</jats:p> </jats:sec> <jats:sec id="sec002"> <jats:title>Objective</jats:title> <jats:p>To evaluate the impact of MRF service for the identification and management DRPs associated to patients’ behavior and to describe pharmaceutical interventions carried out through MRF.</jats:p> </jats:sec> <jats:sec id="sec003"> <jats:title>Methods</jats:title> <jats:p>A pre-post intervention study with a cluster design and one intervention group will be carried out in CPs in the canton of Vaud (Switzerland) for 15 months. Volunteer pharmacists will be trained on the identification and management of DRPs related to patients’ behavior. After training, they will include randomly selected adults taking four or more chronic drugs prescribed for at least three months prior to recruitment. Then, they will conduct three pharmacist-patient face-to-face consultations at 6-month intervals. Tasks will be differentiated by pharmacy technician or pharmacist to triage expired medication or to manage DRPs in a structured manner, respectively. The primary outcome is the identification of DRPs associated to patients’ behavior. Secondary outcomes are to assess patients’ medication knowledge, number of expired medications, interventions carried out by pharmacists and pharmacists’ satisfaction. The study will begin in April 2023 in 19 to 35 pharmacies that will recruit at least 162 patients. A sub analysis will be carried out for patients with 65 years old or over.</jats:p> </jats:sec> <jats:sec id="sec004"> <jats:title>Conclusions</jats:title> <jats:p>The MRF intervention features a training designed for an enhanced evaluation of patient’s behavior towards their medication. The study will allow the assessment and management of DRPs in Swiss CPs with the support of the local health authorities and pharmacist association.</jats:p> </jats:sec> <jats:sec id="sec005"> <jats:title>Trial registration</jats:title> <jats:p>Clinicaltrials.gov <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://clinicaltrials.gov/ct2/show/NCT05348538" xlink:type="simple">NCT05348538</jats:ext-link>.</jats:p> </jats:sec>
dc.language	en
dc.publisher	Public Library of Science (PLoS)
dc.relation.ispartof	PLOS ONE
dc.relation.isbasedon	10.1371/journal.pone.0292037
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.classification	General Science & Technology
dc.title	Evaluation of an enhanced service for medication review with follow up in Swiss community pharmacies: Pre-post study protocol
dc.type	Journal Article
utslib.citation.volume	18
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.date.updated	2023-10-19T05:54:24Z
pubs.issue	10
pubs.publication-status	Published online
pubs.volume	18
utslib.citation.issue	10

Abstract:

Background In Switzerland, 20,000 people are hospitalized each year as result of drug related problems (DRPs). The sources of DRPs can be related to patients’ behavior (i.e., wrong administration) or to health processes (i.e., drug-drug interaction). No community pharmacy (CP) service focus on DRPs related to patients’ behavior is currently recognized or remunerated in Switzerland. A medication review with follow up (MRF) has been developed to evaluate prescription and non-prescription medication. Objective To evaluate the impact of MRF service for the identification and management DRPs associated to patients’ behavior and to describe pharmaceutical interventions carried out through MRF. Methods A pre-post intervention study with a cluster design and one intervention group will be carried out in CPs in the canton of Vaud (Switzerland) for 15 months. Volunteer pharmacists will be trained on the identification and management of DRPs related to patients’ behavior. After training, they will include randomly selected adults taking four or more chronic drugs prescribed for at least three months prior to recruitment. Then, they will conduct three pharmacist-patient face-to-face consultations at 6-month intervals. Tasks will be differentiated by pharmacy technician or pharmacist to triage expired medication or to manage DRPs in a structured manner, respectively. The primary outcome is the identification of DRPs associated to patients’ behavior. Secondary outcomes are to assess patients’ medication knowledge, number of expired medications, interventions carried out by pharmacists and pharmacists’ satisfaction. The study will begin in April 2023 in 19 to 35 pharmacies that will recruit at least 162 patients. A sub analysis will be carried out for patients with 65 years old or over. Conclusions The MRF intervention features a training designed for an enhanced evaluation of patient’s behavior towards their medication. The study will allow the assessment and management of DRPs in Swiss CPs with the support of the local health authorities and pharmacist association. Trial registration Clinicaltrials.gov NCT05348538.

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