Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

Singla, M; Smriti,; Gupta, S; Behal, P; Singh, SK; Preetam, S; Rustagi, S; Bora, J; Mittal, P; Malik, S; Slama, P

Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment

Singla, M Smriti, Gupta, S Behal, P Singh, SK Preetam, S Rustagi, S Bora, J Mittal, P Malik, S Slama, P

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Publisher:: Frontiers
Publication Type:: Journal Article
Citation:: Frontiers in Nutrition, 10, pp. 1258516

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Field	Value	Language
dc.contributor.author	Singla, M
dc.contributor.author	Smriti,
dc.contributor.author	Gupta, S
dc.contributor.author	Behal, P
dc.contributor.author	Singh, SK
dc.contributor.author	Preetam, S
dc.contributor.author	Rustagi, S
dc.contributor.author	Bora, J
dc.contributor.author	Mittal, P
dc.contributor.author	Malik, S
dc.contributor.author	Slama, P
dc.date.accessioned	2024-02-01T06:53:48Z
dc.date.available	2024-02-01T06:53:48Z
dc.identifier.citation	Frontiers in Nutrition, 10, pp. 1258516
dc.identifier.issn	2296-861X
dc.identifier.issn	2296-861X
dc.identifier.uri	http://hdl.handle.net/10453/175238
dc.description.abstract	<jats:p>Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cells in the process. As a result, there is a growing interest in exploring novel therapies that are both effective and less toxic to normal cells. Herbs have long been used as natural remedies for various diseases and conditions. Some herbal compounds exhibit potent anti-cancer properties, making them potential candidates for nutraceutical-based treatments. However, despite their promising efficacy, there are considerable limitations in utilizing herbal preparations due to their poor solubility, low bioavailability, rapid metabolism and excretion, as well as potential interference with other medications. Nanotechnology offers a unique platform to overcome these challenges by encapsulating herbal compounds within nanoparticles. This approach not only increases solubility and stability but also enhances the cellular uptake of nutraceuticals, allowing for controlled and targeted delivery of therapeutic agents directly at tumor sites. By harnessing the power of nanotechnology-enabled therapy, this new frontier in cancer treatment presents an opportunity to minimize toxicity while maximizing efficacy. In conclusion, this manuscript provides compelling evidence for integrating nanotechnology with nutraceuticals derived from herbal sources to optimize cancer therapy outcomes. We explore the roadblocks associated with traditional herbal treatments and demonstrate how nanotechnology can help circumvent these issues, paving the way for safer and more effective cancer interventions in future oncological practice.</jats:p>
dc.language	en
dc.publisher	Frontiers
dc.relation.ispartof	Frontiers in Nutrition
dc.relation.isbasedon	10.3389/fnut.2023.1258516
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1001 Agricultural Biotechnology, 1111 Nutrition and Dietetics
dc.subject.classification	3210 Nutrition and dietetics
dc.title	Unlocking the power of nanomedicine: the future of nutraceuticals in oncology treatment
dc.type	Journal Article
utslib.citation.volume	10
utslib.for	1001 Agricultural Biotechnology
utslib.for	1111 Nutrition and Dietetics
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Public Health
utslib.copyright.status	open_access	*
dc.date.updated	2024-02-01T06:53:47Z
pubs.publication-status	Published online
pubs.volume	10

Abstract:

Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled proliferation of cells that can lead to serious health complications and ultimately death. Conventional therapeutic strategies mainly target rapidly dividing cancer cells, but often indiscriminately harm healthy cells in the process. As a result, there is a growing interest in exploring novel therapies that are both effective and less toxic to normal cells. Herbs have long been used as natural remedies for various diseases and conditions. Some herbal compounds exhibit potent anti-cancer properties, making them potential candidates for nutraceutical-based treatments. However, despite their promising efficacy, there are considerable limitations in utilizing herbal preparations due to their poor solubility, low bioavailability, rapid metabolism and excretion, as well as potential interference with other medications. Nanotechnology offers a unique platform to overcome these challenges by encapsulating herbal compounds within nanoparticles. This approach not only increases solubility and stability but also enhances the cellular uptake of nutraceuticals, allowing for controlled and targeted delivery of therapeutic agents directly at tumor sites. By harnessing the power of nanotechnology-enabled therapy, this new frontier in cancer treatment presents an opportunity to minimize toxicity while maximizing efficacy. In conclusion, this manuscript provides compelling evidence for integrating nanotechnology with nutraceuticals derived from herbal sources to optimize cancer therapy outcomes. We explore the roadblocks associated with traditional herbal treatments and demonstrate how nanotechnology can help circumvent these issues, paving the way for safer and more effective cancer interventions in future oncological practice.

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http://hdl.handle.net/10453/175238