Self-supervised ensembled learning for autism spectrum classification
- Publisher:
- ELSEVIER SCI LTD
- Publication Type:
- Journal Article
- Citation:
- Research in Autism Spectrum Disorders, 2023, 107
- Issue Date:
- 2023-09-01
Closed Access
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1-s2.0-S175094672300123X-main.pdf | Published version | 1.67 MB |
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Purpose: Deep learning has made remarkable progress in classifying autism spectrum disorder (ASD) using neuroimaging data. However, the current methods rely mainly on supervised learning, which requires a large amount of manually labeled data, making it an expensive and difficult task to scale. Methods: To overcome this limitation, we propose a novel ensemble-based framework that learns a transferable and generalizable visual representation from different self-supervised features for the downstream task of ASD classification. This framework dynamically learns a superior representation by aggregating complementary information in the frequency domain from independent self-supervised features with limited data. Additionally, to address the information loss caused by the dimensionality reduction of 3D fMRI data, we propose a thresholding algorithm to optimally extract the most discriminant features from 2D rs-fMRI data. Results: Experimental results demonstrate that the proposed method outperforms previous state-of-the-art methods by 19.69% on the ABIDE-1 dataset with a 10-fold cross-validation accuracy of 94.51%. Conclusion: The proposed method learns a transferrable and generalizable ensembled representation by leveraging complementary information encoded in different self-supervised representations for ASD classification.
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