The high cost of care and limited evidence on cost-effective strategies for Lewy body dementia: systematic review of evidence.

Boland, E; Fitzpatrick, R; Ryan, D; Kane, J; Betzhold, S; Leroi, I; Kinchin, I

The high cost of care and limited evidence on cost-effective strategies for Lewy body dementia: systematic review of evidence.

Boland, E Fitzpatrick, R Ryan, D Kane, J Betzhold, S Leroi, I Kinchin, I

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Publisher:: CAMBRIDGE UNIV PRESS
Publication Type:: Journal Article
Citation:: BJPsych Open, 2024, 10, (1), pp. e20
Issue Date:: 2024-01-05

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Field	Value	Language
dc.contributor.author	Boland, E
dc.contributor.author	Fitzpatrick, R
dc.contributor.author	Ryan, D
dc.contributor.author	Kane, J
dc.contributor.author	Betzhold, S
dc.contributor.author	Leroi, I
dc.contributor.author	Kinchin, I https://orcid.org/0000-0003-0133-2763
dc.date.accessioned	2024-08-06T02:11:46Z
dc.date.available	2024-08-06T02:11:46Z
dc.date.issued	2024-01-05
dc.identifier.citation	BJPsych Open, 2024, 10, (1), pp. e20
dc.identifier.issn	2056-4724
dc.identifier.issn	2056-4724
dc.identifier.uri	http://hdl.handle.net/10453/180065
dc.description.abstract	BACKGROUND: Lewy body dementia (LBD) is a prevalent yet frequently underdiagnosed form of dementia, accounting for up to 15% of all dementia cases. AIMS: This study aims to increase awareness and advocacy for LBD by gathering and critically assessing the economic evidence, including the cost of illness and cost-effectiveness of interventions for managing LBD. METHOD: A systematic literature review was undertaken with EMBASE, Medline, CINAHL, PsycINFO, NHS Economic Evaluation Database and EconLit. This search was supplemented by grey literature on Google Scholar and reviewing the reference lists of identified studies. The papers included in the review were published between 2008 and 2023, and involved participants with LBD (dementia with Lewy bodies or Parkinson's disease dementia), which either addressed the cost of illness or conducted an economic evaluation. RESULTS: Thirteen papers were included, comprising ten cost-of-illness studies and three economic evaluations. The cost of LBD tends to be higher than that of other forms of dementia, such as Alzheimer's disease, and these costs escalate more steeply as the disease progresses. These cost differences may not be solely influenced by the subtype of dementia, but possibly also by patient characteristics like physical and cognitive abilities. Cost-effectiveness of potential interventions for LBD is limited. CONCLUSIONS: Despite numerous drug trials and other interventions for dementia, very few have targeted LBD, let alone explored the cost-effectiveness of such therapies for LBD. This disparity highlights the urgent need for cost-effective strategies and interventions targeting LBD. We propose the establishment of universally accepted standards for LBD research.
dc.format	Electronic
dc.language	eng
dc.publisher	CAMBRIDGE UNIV PRESS
dc.relation.ispartof	BJPsych Open
dc.relation.isbasedon	10.1192/bjo.2023.626
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1103 Clinical Sciences, 1117 Public Health and Health Services
dc.subject.classification	3202 Clinical sciences
dc.subject.classification	4203 Health services and systems
dc.title	The high cost of care and limited evidence on cost-effective strategies for Lewy body dementia: systematic review of evidence.
dc.type	Journal Article
utslib.citation.volume	10
utslib.location.activity	England
utslib.for	1103 Clinical Sciences
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/IMPACCT
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
dc.date.updated	2024-08-06T02:11:44Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	10
utslib.citation.issue	1

Abstract:

BACKGROUND: Lewy body dementia (LBD) is a prevalent yet frequently underdiagnosed form of dementia, accounting for up to 15% of all dementia cases. AIMS: This study aims to increase awareness and advocacy for LBD by gathering and critically assessing the economic evidence, including the cost of illness and cost-effectiveness of interventions for managing LBD. METHOD: A systematic literature review was undertaken with EMBASE, Medline, CINAHL, PsycINFO, NHS Economic Evaluation Database and EconLit. This search was supplemented by grey literature on Google Scholar and reviewing the reference lists of identified studies. The papers included in the review were published between 2008 and 2023, and involved participants with LBD (dementia with Lewy bodies or Parkinson's disease dementia), which either addressed the cost of illness or conducted an economic evaluation. RESULTS: Thirteen papers were included, comprising ten cost-of-illness studies and three economic evaluations. The cost of LBD tends to be higher than that of other forms of dementia, such as Alzheimer's disease, and these costs escalate more steeply as the disease progresses. These cost differences may not be solely influenced by the subtype of dementia, but possibly also by patient characteristics like physical and cognitive abilities. Cost-effectiveness of potential interventions for LBD is limited. CONCLUSIONS: Despite numerous drug trials and other interventions for dementia, very few have targeted LBD, let alone explored the cost-effectiveness of such therapies for LBD. This disparity highlights the urgent need for cost-effective strategies and interventions targeting LBD. We propose the establishment of universally accepted standards for LBD research.

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http://hdl.handle.net/10453/180065