Surface modification and its influence on osseointegration of implants

Publisher:
Academic Press
Publication Type:
Chapter
Citation:
Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine, 2024, pp. 93-111
Issue Date:
2024-01-01
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22941179_14684817330005671.pdfPublished version2.29 MB
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This chapter aims to provide a brief insight into the latest in vivo research related to the applications of multifunctional calcium phosphate coatings on titanium surfaces in dentistry. The prevention of inflammatory responses and promotion of osseointegration and biological fixation are some of the critical requirements for any implants. Consequently, surface modifications through coating deposition on these materials are intended to provide protection against metal ion release that could elicit a negative host response. The research and deposition of calcium phosphate have undergone a revolution, and a greater emphasis will be placed on the incorporation of therapeutic ions, growth factors, stem cells, and antibiotics as multifunctional coatings to reduce the timeframe for implant integration and failure due to postoperative bacterial infections in both healthy and osteoporotic patients.
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