Early Change in Quality of Life in the Treatment of Anorexia Nervosa

Newton, ED; Liu, L; Conti, J; Touyz, S; Arcelus, J; Madden, S; Pike, K; Hay, P

Early Change in Quality of Life in the Treatment of Anorexia Nervosa

Newton, ED Liu, L

Conti, J Touyz, S Arcelus, J Madden, S Pike, K Hay, P

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Publisher:: MDPI
Publication Type:: Journal Article
Citation:: Psych, 6, (1), pp. 288-304

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Field	Value	Language
dc.contributor.author	Newton, ED
dc.contributor.author	Liu, L https://orcid.org/0000-0001-8671-5098
dc.contributor.author	Conti, J
dc.contributor.author	Touyz, S
dc.contributor.author	Arcelus, J
dc.contributor.author	Madden, S
dc.contributor.author	Pike, K
dc.contributor.author	Hay, P
dc.date.accessioned	2024-10-10T03:33:58Z
dc.date.available	2024-10-10T03:33:58Z
dc.identifier.citation	Psych, 6, (1), pp. 288-304
dc.identifier.issn	2624-8611
dc.identifier.issn	2624-8611
dc.identifier.uri	http://hdl.handle.net/10453/181374
dc.description.abstract	<jats:p>This study aimed to examine whether early change in self-reported quality of life (QoL) was a predictor of outcomes in the treatment of anorexia nervosa (AN). Given suggestions that people with AN overestimate their QoL when unwell, we hypothesised that any early change in self-reported QoL, be it an early improvement or early worsening, would predict better outcomes in terms of end-of-treatment body mass index (BMI), eating disorder (ED) psychopathology, and QoL. Participants were 78 adult outpatients engaged in cognitive behaviour therapy for anorexia nervosa (CBT-AN) either with or without the embedded compulsive exercise module “compuLsive Exercise Activity TheraPy” (LEAP). Polynomial regression was utilised to examine the effects of varying combinations of baseline and 10-week self-reported physical-health-relatedr QoL (SF-12; PHRQoL subscale), mental-health-related QoL (SF-12; MHRQoL subscale), and eating-disorder-specific QoL (EDQoL; global, psychological, cognitive/physical, financial, and school/work subscales) on end-of-treatment BMI, ED psychopathology, and QoL. Greater magnitudes of early change in global EDQoL scores, both positive and negative, predicted better MHRQoL but not BMI or ED psychopathology at the end of treatment. Psychological EDQoL ratings also accounted for 38.1% of the variance in end-of-treatment ED psychopathology, although tests examining the 6ratings may be meaningful in predicting treatment outcomes. The positive impact of early worsening in QoL ratings suggests that early QoL ratings are inflated due to denial and poor insight. Clinicians should be reassured that early QoL decline does not indicate treatment failure.</jats:p>
dc.language	en
dc.publisher	MDPI
dc.relation.ispartof	Psych
dc.relation.isbasedon	10.3390/psych6010018
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Early Change in Quality of Life in the Treatment of Anorexia Nervosa
dc.type	Journal Article
utslib.citation.volume	6
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Clinical Psychology
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
dc.date.updated	2024-10-10T03:33:56Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	6
utslib.citation.issue	1

Abstract:

This study aimed to examine whether early change in self-reported quality of life (QoL) was a predictor of outcomes in the treatment of anorexia nervosa (AN). Given suggestions that people with AN overestimate their QoL when unwell, we hypothesised that any early change in self-reported QoL, be it an early improvement or early worsening, would predict better outcomes in terms of end-of-treatment body mass index (BMI), eating disorder (ED) psychopathology, and QoL. Participants were 78 adult outpatients engaged in cognitive behaviour therapy for anorexia nervosa (CBT-AN) either with or without the embedded compulsive exercise module “compuLsive Exercise Activity TheraPy” (LEAP). Polynomial regression was utilised to examine the effects of varying combinations of baseline and 10-week self-reported physical-health-relatedr QoL (SF-12; PHRQoL subscale), mental-health-related QoL (SF-12; MHRQoL subscale), and eating-disorder-specific QoL (EDQoL; global, psychological, cognitive/physical, financial, and school/work subscales) on end-of-treatment BMI, ED psychopathology, and QoL. Greater magnitudes of early change in global EDQoL scores, both positive and negative, predicted better MHRQoL but not BMI or ED psychopathology at the end of treatment. Psychological EDQoL ratings also accounted for 38.1% of the variance in end-of-treatment ED psychopathology, although tests examining the 6ratings may be meaningful in predicting treatment outcomes. The positive impact of early worsening in QoL ratings suggests that early QoL ratings are inflated due to denial and poor insight. Clinicians should be reassured that early QoL decline does not indicate treatment failure.

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http://hdl.handle.net/10453/181374