Effect of a 4-week pulmonary telerehabilitation program for people with respiratory post-acute sequelae of COVID-19–A randomised controlled trial

Reeves, JM; Spencer, LM; Tsai, LL; Baillie, AJ; Han, Y; Leung, RWM; Bishop, J; Troy, LK; Corte, TJ; Teoh, AKY; Peters, M; Barton, C; Jones, L; Alison, JA

Effect of a 4-week pulmonary telerehabilitation program for people with respiratory post-acute sequelae of COVID-19–A randomised controlled trial

Reeves, JM Spencer, LM Tsai, LL Baillie, AJ Han, Y Leung, RWM Bishop, J Troy, LK Corte, TJ Teoh, AKY Peters, M Barton, C Jones, L Alison, JA

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Publisher:: Taylor & Francis
Publication Type:: Journal Article
Citation:: European Journal of Physiotherapy, 2025, ahead-of-print, (ahead-of-print), pp. 1-10
Issue Date:: 2025-01-01

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Field	Value	Language
dc.contributor.author	Reeves, JM
dc.contributor.author	Spencer, LM
dc.contributor.author	Tsai, LL
dc.contributor.author	Baillie, AJ
dc.contributor.author	Han, Y
dc.contributor.author	Leung, RWM
dc.contributor.author	Bishop, J
dc.contributor.author	Troy, LK
dc.contributor.author	Corte, TJ
dc.contributor.author	Teoh, AKY
dc.contributor.author	Peters, M
dc.contributor.author	Barton, C
dc.contributor.author	Jones, L
dc.contributor.author	Alison, JA
dc.date.accessioned	2025-04-30T00:01:22Z
dc.date.available	2025-04-30T00:01:22Z
dc.date.issued	2025-01-01
dc.identifier.citation	European Journal of Physiotherapy, 2025, ahead-of-print, (ahead-of-print), pp. 1-10
dc.identifier.issn	2167-9169
dc.identifier.issn	2167-9177
dc.identifier.uri	http://hdl.handle.net/10453/187109
dc.description.abstract	Purpose: To evaluate a 4-week pulmonary telerehabilitation (PTR) program compared to usual care for people with persistent respiratory post-acute sequelae of COVID-19 (PASC). Methods: A multi-centre randomised controlled trial with remote assessment and assessor blinding. Participants were randomised 1:1 to 4-weeks, twice-weekly PTR or usual care (Control Group (CG)). PTR exercise intensity was titrated based on fatigue and dyspnoea. After the control period, participants in CG could cross-over into PTR to form a combined group (PTR-X). Primary outcome: 1-minute sit-to-stand test (1-minSTST). Secondary outcomes: 5-repetition sit-to-stand test; Montreal Cognitive Assessment blind-version; COVID-19 Yorkshire Rehabilitation Scale; COPD Assessment Test; 36-Item Short-Form Health Survey; Hospital Anxiety and Depression Scale; Fatigue Severity Scale; Kessler Psychological Distress Scale, all assessed at baseline and following intervention or control periods. Data were analysed using a linear mixed effects model. Results: Of 50 participants recruited, 39 completed the study (PTR group n = 14, CG n = 25). There were no statistically significant between-group differences in any outcomes. For the PTR-X group (n = 27) there was a statistically significant within-group improvement in 1-minSTST (2.4 repetitions, 95%CI 0.6–4.2). Conclusions: A 4-week (8 session) PTR intervention for respiratory PASC showed no significant between-groups differences suggesting that longer PTR programs or alternative interventions should be evaluated.
dc.language	en
dc.publisher	Taylor & Francis
dc.relation.ispartof	European Journal of Physiotherapy
dc.relation.isbasedon	10.1080/21679169.2025.2479676
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.classification	3202 Clinical sciences
dc.subject.classification	4201 Allied health and rehabilitation science
dc.subject.classification	4207 Sports science and exercise
dc.title	Effect of a 4-week pulmonary telerehabilitation program for people with respiratory post-acute sequelae of COVID-19–A randomised controlled trial
dc.type	Journal Article
utslib.citation.volume	ahead-of-print
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Physiotherapy
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated	2025-04-30T00:01:18Z
pubs.issue	ahead-of-print
pubs.publication-status	Published
pubs.volume	ahead-of-print
utslib.citation.issue	ahead-of-print

Abstract:

Purpose: To evaluate a 4-week pulmonary telerehabilitation (PTR) program compared to usual care for people with persistent respiratory post-acute sequelae of COVID-19 (PASC). Methods: A multi-centre randomised controlled trial with remote assessment and assessor blinding. Participants were randomised 1:1 to 4-weeks, twice-weekly PTR or usual care (Control Group (CG)). PTR exercise intensity was titrated based on fatigue and dyspnoea. After the control period, participants in CG could cross-over into PTR to form a combined group (PTR-X). Primary outcome: 1-minute sit-to-stand test (1-minSTST). Secondary outcomes: 5-repetition sit-to-stand test; Montreal Cognitive Assessment blind-version; COVID-19 Yorkshire Rehabilitation Scale; COPD Assessment Test; 36-Item Short-Form Health Survey; Hospital Anxiety and Depression Scale; Fatigue Severity Scale; Kessler Psychological Distress Scale, all assessed at baseline and following intervention or control periods. Data were analysed using a linear mixed effects model. Results: Of 50 participants recruited, 39 completed the study (PTR group n = 14, CG n = 25). There were no statistically significant between-group differences in any outcomes. For the PTR-X group (n = 27) there was a statistically significant within-group improvement in 1-minSTST (2.4 repetitions, 95%CI 0.6–4.2). Conclusions: A 4-week (8 session) PTR intervention for respiratory PASC showed no significant between-groups differences suggesting that longer PTR programs or alternative interventions should be evaluated.

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http://hdl.handle.net/10453/187109