Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: Impact on general and mental health, quality of life and five-year mortality

Inglis, SC; Lewsey, JD; Lowe, GDO; Jhund, P; Gillies, M; Stewart, S; Capewell, S; Macintyre, K; McMurray, JJV

Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: Impact on general and mental health, quality of life and five-year mortality

Inglis, SC

Lewsey, JD Lowe, GDO Jhund, P Gillies, M Stewart, S Capewell, S Macintyre, K

McMurray, JJV

Permalink

Publication Type:: Journal Article
Citation:: International Journal of Cardiology, 2013, 167 (5), pp. 2149 - 2155
Issue Date:: 2013-09-01

Open Access

Copyright Clearance Process

Recently Added
In Progress
Open Access

This item is open access.

Adobe PDF

Download full textAdobe PDF (283.53 kB)

View on publisher's site

View statistics

Full metadata record

Field	Value	Language
dc.contributor.author	Inglis, SC https://orcid.org/0000-0002-1331-5912	en_US
dc.contributor.author	Lewsey, JD	en_US
dc.contributor.author	Lowe, GDO	en_US
dc.contributor.author	Jhund, P	en_US
dc.contributor.author	Gillies, M	en_US
dc.contributor.author	Stewart, S	en_US
dc.contributor.author	Capewell, S	en_US
dc.contributor.author	Macintyre, K https://orcid.org/0000-0003-2741-0467	en_US
dc.contributor.author	McMurray, JJV	en_US
dc.date.available	2012-05-27	en_US
dc.date.issued	2013-09-01	en_US
dc.identifier.citation	International Journal of Cardiology, 2013, 167 (5), pp. 2149 - 2155	en_US
dc.identifier.issn	0167-5273	en_US
dc.identifier.uri	http://hdl.handle.net/10453/26364
dc.description.abstract	Background: Angina and intermittent claudication impair function and mobility and reduce health-related quality of life. Both symptoms have similar etiology, yet the physical and psychological impacts of these symptoms are rarely studied in community-based cohorts or in individuals with isolated symptoms. Methods: The 2003 Scottish Health Survey was a cross-sectional survey which enrolled a random sample of individuals aged 16-95 years living in Scotland. The Rose Angina Questionnaire, the Edinburgh Claudication Questionnaire, the Short Form-12 (SF-12) and the General Health Questionnaire were completed. Self-assessed general health was reported. Survey results were linked to national death records and mortality at five years was calculated. Subjects with isolated angina or intermittent claudication and neither symptom were compared (22 participants with both symptoms were excluded); 7403 participants (aged ≥ 16 years) were included. Results: Participants with angina (n = 205; 60 ± 15 years; 45% male) rated their general health worse and were more likely to have a potential mental-health problem than those with intermittent claudication (n = 173; 61 ± 15 years; 41% male). Mean (standard deviation) physical and mental component scores on the SF-12 were higher for participants with intermittent claudication relative to those with angina (physical component score: 42.3 (10.6) vs. 35.0 (11.7), p < 0.001; mental component score: 52.3 (8.5) vs. 46.5 (11.7), p = 0.001). There was an observed absolute difference in five-year mortality of 4.8% (angina 12.3%, 95% CI 8.5-17.6; intermittent claudication 7.5%, 95% CI 4.4-12.6) although not statistically significant (p = 0.16). Conclusions: Both intermittent claudication and angina adversely impact general and mental health and survival, even in a relatively young, community-based cohort. © 2012 Elsevier Ireland Ltd.	en_US
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT0472699
dc.relation.ispartof	International Journal of Cardiology	en_US
dc.relation.isbasedon	10.1016/j.ijcard.2012.05.099	en_US
dc.subject.classification	Cardiovascular System & Hematology	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Angina Pectoris	en_US
dc.subject.mesh	Intermittent Claudication	en_US
dc.subject.mesh	Health Surveys	en_US
dc.subject.mesh	Survival Rate	en_US
dc.subject.mesh	Cohort Studies	en_US
dc.subject.mesh	Cross-Sectional Studies	en_US
dc.subject.mesh	Mental Health	en_US
dc.subject.mesh	Health Status	en_US
dc.subject.mesh	Quality of Life	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Aged, 80 and over	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Scotland	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Young Adult	en_US
dc.title	Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: Impact on general and mental health, quality of life and five-year mortality	en_US
dc.type	Journal Article
utslib.citation.volume	5	en_US
utslib.citation.volume	167	en_US
utslib.for	1102 Cardiorespiratory Medicine and Haematology	en_US
utslib.for	1117 Public Health and Health Services	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/IMPACCT
utslib.copyright.status	open_access
dcterms.license	This work is distributed under a Creative Commons Attribution license (CC BY) http://creativecommons.org/licenses/by/3.0/
pubs.issue	5	en_US
pubs.publication-status	Published	en_US
pubs.volume	167	en_US

Abstract:

Background: Angina and intermittent claudication impair function and mobility and reduce health-related quality of life. Both symptoms have similar etiology, yet the physical and psychological impacts of these symptoms are rarely studied in community-based cohorts or in individuals with isolated symptoms. Methods: The 2003 Scottish Health Survey was a cross-sectional survey which enrolled a random sample of individuals aged 16-95 years living in Scotland. The Rose Angina Questionnaire, the Edinburgh Claudication Questionnaire, the Short Form-12 (SF-12) and the General Health Questionnaire were completed. Self-assessed general health was reported. Survey results were linked to national death records and mortality at five years was calculated. Subjects with isolated angina or intermittent claudication and neither symptom were compared (22 participants with both symptoms were excluded); 7403 participants (aged ≥ 16 years) were included. Results: Participants with angina (n = 205; 60 ± 15 years; 45% male) rated their general health worse and were more likely to have a potential mental-health problem than those with intermittent claudication (n = 173; 61 ± 15 years; 41% male). Mean (standard deviation) physical and mental component scores on the SF-12 were higher for participants with intermittent claudication relative to those with angina (physical component score: 42.3 (10.6) vs. 35.0 (11.7), p < 0.001; mental component score: 52.3 (8.5) vs. 46.5 (11.7), p = 0.001). There was an observed absolute difference in five-year mortality of 4.8% (angina 12.3%, 95% CI 8.5-17.6; intermittent claudication 7.5%, 95% CI 4.4-12.6) although not statistically significant (p = 0.16). Conclusions: Both intermittent claudication and angina adversely impact general and mental health and survival, even in a relatively young, community-based cohort. © 2012 Elsevier Ireland Ltd.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/26364