Identifying masked uncontrolled hypertension in the community pharmacy setting

Sabater-Hernández, D; Sendra-Lillo, J; Jiménez-Monleón, JJ; Benrimoj, SI; Durks, D; Martínez-Martínez, F; De La Sierra, A

Identifying masked uncontrolled hypertension in the community pharmacy setting

Sabater-Hernández, D

Sendra-Lillo, J Jiménez-Monleón, JJ Benrimoj, SI

Durks, D Martínez-Martínez, F De La Sierra, A

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Publication Type:: Journal Article
Citation:: Blood Pressure Monitoring, 2015, 20 (3), pp. 138 - 143
Issue Date:: 2015-12-01

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Field	Value	Language
dc.contributor.author	Sabater-Hernández, D https://orcid.org/0000-0001-7419-8740	en_US
dc.contributor.author	Sendra-Lillo, J	en_US
dc.contributor.author	Jiménez-Monleón, JJ	en_US
dc.contributor.author	Benrimoj, SI https://orcid.org/0000-0001-9768-7838	en_US
dc.contributor.author	Durks, D	en_US
dc.contributor.author	Martínez-Martínez, F	en_US
dc.contributor.author	De La Sierra, A	en_US
dc.date.available	2020-05-25T19:25:16Z
dc.date.issued	2015-12-01	en_US
dc.identifier.citation	Blood Pressure Monitoring, 2015, 20 (3), pp. 138 - 143	en_US
dc.identifier.issn	1359-5237	en_US
dc.identifier.uri	http://hdl.handle.net/10453/32244
dc.description.abstract	© 2015 Wolters Kluwer Health, Inc. Masked uncontrolled hypertension (MUCH) is associated with an increased cardiovascular risk. This condition is frequent in the community pharmacy (i.e., CP-MUCH), but there is no evidence on the factors associated with its presence in that setting. The aim of this analysis was to explore these factors. A sample of 98 treated hypertensive patients from the MEPAFAR study, with normal community pharmacy blood pressure (CPBP <135/85 mmHg), were analyzed. Blood pressure (BP) was also measured at home (4 days) and monitored for 24 h. CP-MUCH was identified when either ambulatory (daytime) or home BP averages were equal to or higher than 135/85 mmHg. A multivariate logistic regression analysis was carried out to identify the factors associated with CP-MUCH. The prevalence of CP-MUCH tends to be higher as systolic and diastolic CPBP increase, reaching 47% in patients with both systolicand diastolic CPBP equal to or higher than 123 mmHg and 79 mmHg, respectively.The multivariate regression analysis showed only systolic CPBP as an independent factor of CP-MUCH [≥123 mmHg: odds ratio=16.46 (P=0.012); from 115 to 122.9 mmHg: odds ratio=10.74 (P=0.036); systolic CPBP <115 mmHg as the reference]. Further assessment, using ambulatory and/or home BP monitoring, is recommended in patients with normal CPBP, but systolic CPBP equal to or higher than 115 mmHg. A more feasible approach would be evaluating patients with systolic CPBP equal to or higher than 123 mmHg and diastolic CPBP equal to or higher than 79 mmHg.	en_US
dc.relation.ispartof	Blood Pressure Monitoring	en_US
dc.relation.isbasedon	10.1097/MBP.0000000000000105	en_US
dc.subject.classification	Cardiovascular System & Hematology	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Hypertension	en_US
dc.subject.mesh	Blood Pressure Monitoring, Ambulatory	en_US
dc.subject.mesh	Blood Pressure	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Pharmacies	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.title	Identifying masked uncontrolled hypertension in the community pharmacy setting	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	20	en_US
utslib.for	1103 Clinical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Students
utslib.copyright.status	open_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	20	en_US

Abstract:

© 2015 Wolters Kluwer Health, Inc. Masked uncontrolled hypertension (MUCH) is associated with an increased cardiovascular risk. This condition is frequent in the community pharmacy (i.e., CP-MUCH), but there is no evidence on the factors associated with its presence in that setting. The aim of this analysis was to explore these factors. A sample of 98 treated hypertensive patients from the MEPAFAR study, with normal community pharmacy blood pressure (CPBP <135/85 mmHg), were analyzed. Blood pressure (BP) was also measured at home (4 days) and monitored for 24 h. CP-MUCH was identified when either ambulatory (daytime) or home BP averages were equal to or higher than 135/85 mmHg. A multivariate logistic regression analysis was carried out to identify the factors associated with CP-MUCH. The prevalence of CP-MUCH tends to be higher as systolic and diastolic CPBP increase, reaching 47% in patients with both systolicand diastolic CPBP equal to or higher than 123 mmHg and 79 mmHg, respectively.The multivariate regression analysis showed only systolic CPBP as an independent factor of CP-MUCH [≥123 mmHg: odds ratio=16.46 (P=0.012); from 115 to 122.9 mmHg: odds ratio=10.74 (P=0.036); systolic CPBP <115 mmHg as the reference]. Further assessment, using ambulatory and/or home BP monitoring, is recommended in patients with normal CPBP, but systolic CPBP equal to or higher than 115 mmHg. A more feasible approach would be evaluating patients with systolic CPBP equal to or higher than 123 mmHg and diastolic CPBP equal to or higher than 79 mmHg.

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http://hdl.handle.net/10453/32244