Zinc oxide nanoparticles induce cell filamentation in escherichia coli

Gunawan, C; Teoh, WY; Ricardo; Marquis, CP; Amal, R

Zinc oxide nanoparticles induce cell filamentation in escherichia coli

Gunawan, C

Teoh, WY Ricardo Marquis, CP Amal, R

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Publication Type:: Journal Article
Citation:: Particle and Particle Systems Characterization, 2013, 30 (4), pp. 375 - 380
Issue Date:: 2013-04-01

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Field	Value	Language
dc.contributor.author	Gunawan, C https://orcid.org/0000-0002-2957-1347	en_US
dc.contributor.author	Teoh, WY	en_US
dc.contributor.author	Ricardo	en_US
dc.contributor.author	Marquis, CP	en_US
dc.contributor.author	Amal, R	en_US
dc.date.issued	2013-04-01	en_US
dc.identifier.citation	Particle and Particle Systems Characterization, 2013, 30 (4), pp. 375 - 380	en_US
dc.identifier.issn	0934-0866	en_US
dc.identifier.uri	http://hdl.handle.net/10453/36314
dc.description.abstract	Zinc oxide nanoparticles (ZnO NPs) induce morphological transformation of Escherichia coli from its native rod-shape of ≈2-4 μm to filamentous cells of 20-40 μm in length. The transient response can only be observed at up to 3.5 h proliferation, beyond which the cytotoxic effect is neutralized and the rod-shape is restored. The filamentation is part of the bacterium SOS response to the Trojan horse-type internalization of undissolved ZnO solids. In the absence of ZnO solids, no cell filamentation can be observed from the leached soluble zinc fraction or dissolved zinc salt. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.	en_US
dc.relation.ispartof	Particle and Particle Systems Characterization	en_US
dc.relation.isbasedon	10.1002/ppsc.201200152	en_US
dc.subject.classification	Chemical Engineering	en_US
dc.title	Zinc oxide nanoparticles induce cell filamentation in escherichia coli	en_US
dc.type	Journal Article
utslib.citation.volume	4	en_US
utslib.citation.volume	30	en_US
utslib.for	029903 Medical Physics	en_US
utslib.for	0299 Other Physical Sciences	en_US
utslib.for	0904 Chemical Engineering	en_US
utslib.for	0913 Mechanical Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	closed_access
pubs.issue	4	en_US
pubs.publication-status	Published	en_US
pubs.volume	30	en_US

Abstract:

Zinc oxide nanoparticles (ZnO NPs) induce morphological transformation of Escherichia coli from its native rod-shape of ≈2-4 μm to filamentous cells of 20-40 μm in length. The transient response can only be observed at up to 3.5 h proliferation, beyond which the cytotoxic effect is neutralized and the rod-shape is restored. The filamentation is part of the bacterium SOS response to the Trojan horse-type internalization of undissolved ZnO solids. In the absence of ZnO solids, no cell filamentation can be observed from the leached soluble zinc fraction or dissolved zinc salt. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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http://hdl.handle.net/10453/36314