Gastroenterologist perceptions of faecal microbiota transplantation

Paramsothy, S; Walsh, AJ; Borody, T; Samuel, D; Van Den Bogaerde, J; Leong, RWL; Connor, S; Ng, W; Mitchell, HM; Kaakoush, NO; Kamm, MA

Gastroenterologist perceptions of faecal microbiota transplantation

Paramsothy, S Walsh, AJ Borody, T

Samuel, D Van Den Bogaerde, J Leong, RWL Connor, S Ng, W Mitchell, HM Kaakoush, NO Kamm, MA

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Publication Type:: Journal Article
Citation:: World Journal of Gastroenterology, 2015, 21 (38), pp. 10907 - 10914
Issue Date:: 2015-01-01

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Field	Value	Language
dc.contributor.author	Paramsothy, S	en_US
dc.contributor.author	Walsh, AJ	en_US
dc.contributor.author	Borody, T https://orcid.org/0000-0002-0519-4698	en_US
dc.contributor.author	Samuel, D	en_US
dc.contributor.author	Van Den Bogaerde, J	en_US
dc.contributor.author	Leong, RWL	en_US
dc.contributor.author	Connor, S	en_US
dc.contributor.author	Ng, W	en_US
dc.contributor.author	Mitchell, HM	en_US
dc.contributor.author	Kaakoush, NO	en_US
dc.contributor.author	Kamm, MA	en_US
dc.date.available	2015-08-31	en_US
dc.date.issued	2015-01-01	en_US
dc.identifier.citation	World Journal of Gastroenterology, 2015, 21 (38), pp. 10907 - 10914	en_US
dc.identifier.issn	1007-9327	en_US
dc.identifier.uri	http://hdl.handle.net/10453/41587
dc.description.abstract	© 2015 Baishideng Publishing Group Inc. All rights reserved. AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation (FMT). METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed. RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT, 8% more than once. Ninety percent would refer patients with Clostridium difficile infection (CDI) for FMT if easily available, 37% for ulcerative colitis, 13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication, including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic, 17% nasoduodenal, 13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence, 12% infection risk, 10% non infectious adverse effects/lack of safety data, 10% aesthetic, 10% lack of efficacy, 4% disease exacerbation, and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution. CONCLUSION: Despite general enthusiasm, most gastroenterologists have limited experience with, or access to, FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required.	en_US
dc.relation.ispartof	World Journal of Gastroenterology	en_US
dc.relation.isbasedon	10.3748/wjg.v21.i38.10907	en_US
dc.subject.classification	Gastroenterology & Hepatology	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Clostridium difficile	en_US
dc.subject.mesh	Enterocolitis, Pseudomembranous	en_US
dc.subject.mesh	Colitis, Ulcerative	en_US
dc.subject.mesh	Crohn Disease	en_US
dc.subject.mesh	Irritable Bowel Syndrome	en_US
dc.subject.mesh	Attitude of Health Personnel	en_US
dc.subject.mesh	Perception	en_US
dc.subject.mesh	Gastroenterology	en_US
dc.subject.mesh	Health Services Accessibility	en_US
dc.subject.mesh	Australia	en_US
dc.subject.mesh	Fecal Microbiota Transplantation	en_US
dc.title	Gastroenterologist perceptions of faecal microbiota transplantation	en_US
dc.type	Journal Article
utslib.citation.volume	38	en_US
utslib.citation.volume	21	en_US
utslib.for	1103 Clinical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
utslib.copyright.status	open_access
pubs.issue	38	en_US
pubs.publication-status	Published	en_US
pubs.volume	21	en_US

Abstract:

© 2015 Baishideng Publishing Group Inc. All rights reserved. AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation (FMT). METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed. RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT, 8% more than once. Ninety percent would refer patients with Clostridium difficile infection (CDI) for FMT if easily available, 37% for ulcerative colitis, 13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication, including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic, 17% nasoduodenal, 13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence, 12% infection risk, 10% non infectious adverse effects/lack of safety data, 10% aesthetic, 10% lack of efficacy, 4% disease exacerbation, and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution. CONCLUSION: Despite general enthusiasm, most gastroenterologists have limited experience with, or access to, FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required.

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http://hdl.handle.net/10453/41587