Timing of intravenous administration set changes: a systematic review.

Gillies, D; O'Riordan, L; Wallen, M; Rankin, K; Morrison, A; Nagy, S

Timing of intravenous administration set changes: a systematic review.

Gillies, D O'Riordan, L Wallen, M Rankin, K Morrison, A Nagy, S

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Publication Type:: Journal Article
Citation:: Infect Control Hosp Epidemiol, 2004, 25 (3), pp. 240 - 250
Issue Date:: 2004-03

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Field	Value	Language
dc.contributor.author	Gillies, D	en_US
dc.contributor.author	O'Riordan, L	en_US
dc.contributor.author	Wallen, M	en_US
dc.contributor.author	Rankin, K	en_US
dc.contributor.author	Morrison, A	en_US
dc.contributor.author	Nagy, S	en_US
dc.date.issued	2004-03	en_US
dc.identifier.citation	Infect Control Hosp Epidemiol, 2004, 25 (3), pp. 240 - 250	en_US
dc.identifier.issn	0899-823X	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4646
dc.description.abstract	OBJECTIVE: To determine the optimal time interval for the routine replacement of intravenous administration sets when crystalloids or parenteral nutrition are administered via a central or peripheral catheter in an acute care setting. DESIGN: Systematic review of all randomized or systematically allocated controlled trials addressing the frequency of replacing intravenous administration sets. METHODS: The Cochrane Controlled Trials Register (June 2001) and the Ovid databases (Medline, CINAHL, and CancerLit-July 2001) were searched. Bibliographies, relevant conference proceedings, and any product information were also checked for references. RESULTS: Eighteen studies were selected for review. The 12 included studies were separated into 3 intravenous administration set change comparisons: 24 hours versus 48 hours or more; 48 hours versus 72 hours or more; and 72 hours versus 96 hours or more. There was good evidence that changing intravenous administration sets every 72 hours or more does not increase the risk of infusate-related bloodstream infection (BSI) in patients with central or peripheral catheters and a fair level of evidence that it does not increase the risk of catheter-related BSI. There were insufficient data regarding the incidence of BSI among patients receiving parenteral nutrition, particularly lipid-containing parenteral nutrition. CONCLUSIONS: It appears that intravenous administration sets containing crystalloids can be changed in patients with central or peripheral catheters every 72 hours or more without increasing the risk of BSI. However, it is not possible to conclude that intravenous administration sets containing parenteral nutrition, particularly lipid-containing parenteral nutrition, can be changed at this interval.	en_US
dc.language	eng	en_US
dc.relation.ispartof	Infect Control Hosp Epidemiol	en_US
dc.relation.isbasedon	10.1086/502385	en_US
dc.subject.classification	Epidemiology	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Bacteremia	en_US
dc.subject.mesh	Cross Infection	en_US
dc.subject.mesh	Rehydration Solutions	en_US
dc.subject.mesh	Catheterization, Central Venous	en_US
dc.subject.mesh	Parenteral Nutrition	en_US
dc.subject.mesh	Infusions, Intravenous	en_US
dc.subject.mesh	Catheters, Indwelling	en_US
dc.subject.mesh	Time Factors	en_US
dc.subject.mesh	Randomized Controlled Trials as Topic	en_US
dc.title	Timing of intravenous administration set changes: a systematic review.	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	25	en_US
utslib.location.activity	United States	en_US
utslib.for	1110 Nursing	en_US
utslib.for	11 Medical and Health Sciences	en_US
dc.location.activity	Monterey Bay, USA
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	25	en_US

Abstract:

OBJECTIVE: To determine the optimal time interval for the routine replacement of intravenous administration sets when crystalloids or parenteral nutrition are administered via a central or peripheral catheter in an acute care setting. DESIGN: Systematic review of all randomized or systematically allocated controlled trials addressing the frequency of replacing intravenous administration sets. METHODS: The Cochrane Controlled Trials Register (June 2001) and the Ovid databases (Medline, CINAHL, and CancerLit-July 2001) were searched. Bibliographies, relevant conference proceedings, and any product information were also checked for references. RESULTS: Eighteen studies were selected for review. The 12 included studies were separated into 3 intravenous administration set change comparisons: 24 hours versus 48 hours or more; 48 hours versus 72 hours or more; and 72 hours versus 96 hours or more. There was good evidence that changing intravenous administration sets every 72 hours or more does not increase the risk of infusate-related bloodstream infection (BSI) in patients with central or peripheral catheters and a fair level of evidence that it does not increase the risk of catheter-related BSI. There were insufficient data regarding the incidence of BSI among patients receiving parenteral nutrition, particularly lipid-containing parenteral nutrition. CONCLUSIONS: It appears that intravenous administration sets containing crystalloids can be changed in patients with central or peripheral catheters every 72 hours or more without increasing the risk of BSI. However, it is not possible to conclude that intravenous administration sets containing parenteral nutrition, particularly lipid-containing parenteral nutrition, can be changed at this interval.

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http://hdl.handle.net/10453/4646