Microarrays and stage conversion in Toxoplasma gondii

Ellis, J; Sinclair, D; Morrison, D

Microarrays and stage conversion in Toxoplasma gondii

Ellis, J

Sinclair, D Morrison, D

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Publication Type:: Journal Article
Citation:: Trends in Parasitology, 2004, 20 (6), pp. 288 - 295
Issue Date:: 2004-06-01

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Field	Value	Language
dc.contributor.author	Ellis, J https://orcid.org/0000-0001-7328-4831	en_US
dc.contributor.author	Sinclair, D	en_US
dc.contributor.author	Morrison, D	en_US
dc.date.issued	2004-06-01	en_US
dc.identifier.citation	Trends in Parasitology, 2004, 20 (6), pp. 288 - 295	en_US
dc.identifier.issn	1471-4922	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4707
dc.description.abstract	Microarray technology is emerging as a powerful method for the study of those changes in gene expression that occur when a parasite converts from one life cycle stage to another. The use of appropriate experimental design and data analysis methodologies is essential if this technology is to be correctly exploited. In this review, the study of stage conversion in the transformation of Toxoplasma gondii tachyzoites into bradyzoites is considered as an example of where the application of microarrays is revealing exciting new knowledge on underlying molecular mechanisms. The more general application of microarrays in parasitology is also discussed.	en_US
dc.relation.ispartof	Trends in Parasitology	en_US
dc.relation.isbasedon	10.1016/j.pt.2004.04.006	en_US
dc.subject.classification	Mycology & Parasitology	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Toxoplasma	en_US
dc.subject.mesh	Toxoplasmosis	en_US
dc.subject.mesh	Oligonucleotide Array Sequence Analysis	en_US
dc.title	Microarrays and stage conversion in Toxoplasma gondii	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	20	en_US
utslib.for	070708 Veterinary Parasitology	en_US
utslib.for	06 Biological Sciences	en_US
utslib.for	07 Agricultural and Veterinary Sciences	en_US
utslib.for	11 Medical and Health Sciences	en_US
dc.location.activity	England
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/DVC (Corporate Services)
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	20	en_US

Abstract:

Microarray technology is emerging as a powerful method for the study of those changes in gene expression that occur when a parasite converts from one life cycle stage to another. The use of appropriate experimental design and data analysis methodologies is essential if this technology is to be correctly exploited. In this review, the study of stage conversion in the transformation of Toxoplasma gondii tachyzoites into bradyzoites is considered as an example of where the application of microarrays is revealing exciting new knowledge on underlying molecular mechanisms. The more general application of microarrays in parasitology is also discussed.

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http://hdl.handle.net/10453/4707