Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues

Ung, AT; Pyne, SG; Batenburg-Nguyen, U; Davis, AS; Sherif, A; Bischoff, F; Lesage, ASJ

Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues

Ung, AT

Pyne, SG Batenburg-Nguyen, U Davis, AS Sherif, A Bischoff, F Lesage, ASJ

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Publication Type:: Journal Article
Citation:: Tetrahedron, 2005, 61 (7), pp. 1803 - 1812
Issue Date:: 2005-02-14

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Field	Value	Language
dc.contributor.author	Ung, AT https://orcid.org/0000-0002-5665-0702	en_US
dc.contributor.author	Pyne, SG	en_US
dc.contributor.author	Batenburg-Nguyen, U	en_US
dc.contributor.author	Davis, AS	en_US
dc.contributor.author	Sherif, A	en_US
dc.contributor.author	Bischoff, F	en_US
dc.contributor.author	Lesage, ASJ	en_US
dc.date.issued	2005-02-14	en_US
dc.identifier.citation	Tetrahedron, 2005, 61 (7), pp. 1803 - 1812	en_US
dc.identifier.issn	0040-4020	en_US
dc.identifier.uri	http://hdl.handle.net/10453/8456
dc.description.abstract	The conformationally restricted glutamate analogues, 4-aryl-1-amino-2- cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of 12a and 12b indicates that both compounds are modest antagonists at mGluR2. © 2004 Elsevier Ltd. All rights reserved.	en_US
dc.relation.ispartof	Tetrahedron	en_US
dc.relation.isbasedon	10.1016/j.tet.2004.12.024	en_US
dc.subject.classification	Organic Chemistry	en_US
dc.title	Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues	en_US
dc.type	Journal Article
utslib.citation.volume	7	en_US
utslib.citation.volume	61	en_US
utslib.for	0305 Organic Chemistry	en_US
utslib.for	0304 Medicinal and Biomolecular Chemistry	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CCET - Centre for Clean Energy Technology
utslib.copyright.status	closed_access
pubs.issue	7	en_US
pubs.publication-status	Published	en_US
pubs.volume	61	en_US

Abstract:

The conformationally restricted glutamate analogues, 4-aryl-1-amino-2- cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of 12a and 12b indicates that both compounds are modest antagonists at mGluR2. © 2004 Elsevier Ltd. All rights reserved.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/8456