Engineering miniaturized hair cell sensors for auditory system

Asadnia, M; Kottapalli, AGP; Warkiani, ME; Miao, JM; Triantafyllou, MS

Engineering miniaturized hair cell sensors for auditory system

Asadnia, M Kottapalli, AGP Warkiani, ME

Miao, JM Triantafyllou, MS

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Publication Type:: Conference Proceeding
Citation:: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2017, 0 pp. 1173 - 1176
Issue Date:: 2017-02-23

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Field	Value	Language
dc.contributor.author	Asadnia, M	en_US
dc.contributor.author	Kottapalli, AGP	en_US
dc.contributor.author	Warkiani, ME https://orcid.org/0000-0002-4184-1944	en_US
dc.contributor.author	Miao, JM	en_US
dc.contributor.author	Triantafyllou, MS	en_US
dc.date.issued	2017-02-23	en_US
dc.identifier.citation	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2017, 0 pp. 1173 - 1176	en_US
dc.identifier.isbn	9781509050789	en_US
dc.identifier.issn	1084-6999	en_US
dc.identifier.uri	http://hdl.handle.net/10453/127310
dc.description.abstract	© 2017 IEEE. Mechanosensory haircells are well-evolved biological sensors found in nature. In this paper, we present a novel artificial NEMS stereovilli sensor developed through novel fabrication techniques. The NEMS stereovilli sensor fabrication combines soft-polymer material synthesis methods and nanofiber generation techniques with conventional microfabrication methods to form novel flow sensors. The sensor fabrication mainly consists of three major steps which are 1) fabrication of artificial stereovilli of varying aspect ratios, 2) formation of nanofiber tip-links through electrospinning of PVDF material and 3) development of biomimetic HA-MA hydrogel cupula. These artificial sensors closely mimic stereovilli and achieve ultrahigh sensitivities through a biomimetic design. The sensors achieve a sensitivity and threshold detection limit of 300 mV/(m/s) and 8 μm/s, respectively.	en_US
dc.relation.ispartof	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)	en_US
dc.relation.isbasedon	10.1109/MEMSYS.2017.7863624	en_US
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Engineering miniaturized hair cell sensors for auditory system	en_US
dc.type	Conference Proceeding
utslib.citation.volume	0	en_US
utslib.for	0903 Biomedical Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access	*
pubs.publication-status	Published	en_US
pubs.volume	0	en_US

Abstract:

© 2017 IEEE. Mechanosensory haircells are well-evolved biological sensors found in nature. In this paper, we present a novel artificial NEMS stereovilli sensor developed through novel fabrication techniques. The NEMS stereovilli sensor fabrication combines soft-polymer material synthesis methods and nanofiber generation techniques with conventional microfabrication methods to form novel flow sensors. The sensor fabrication mainly consists of three major steps which are 1) fabrication of artificial stereovilli of varying aspect ratios, 2) formation of nanofiber tip-links through electrospinning of PVDF material and 3) development of biomimetic HA-MA hydrogel cupula. These artificial sensors closely mimic stereovilli and achieve ultrahigh sensitivities through a biomimetic design. The sensors achieve a sensitivity and threshold detection limit of 300 mV/(m/s) and 8 μm/s, respectively.

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http://hdl.handle.net/10453/127310