School of Biomedical Engineering

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Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice.

Hjorth, M Egan, CL Telles, GD Pal, M Gallego-Ortega, D Fuller, OK McLennan, ED Gillis, RD Oh, TG Muscat, GEO Tegegne, S Mah, MSM Skhinas, J Estevez, E Adams, TE McKay, MJ Molloy, M Watt, KI Qian, H Gregorevic, P Cox, TR Hojman, P Midtgaard, J Christensen, JF Friedrichsen, M Iozzo, RV Sloan, EK Drew, BG Wojtaszewski, JFP Whitham, M Febbraio, MA

PURPOSE: Regular exercise can reduce incidence and progression of breast cancer, but the mechanisms for such effects are not fully understood. The purpose of this study was to examine the mechanism...

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Reference Values of Handgrip and Lower Extremity Strength for Vietnamese Men and Women: The Vietnam Osteoporosis Study.

Do, KT Hoang, DK Luong, QN Nguyen, HG Do, AT Ho-Pham, LT Nguyen, TV

BACKGROUND: Falls and sarcopenia are significant public health issues in Vietnam. Despite muscle strength being a critical predictor for these conditions, reference data on muscle strength within t...

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In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS).

Don, EK Maschirow, A Radford, RAW Scherer, NM Vidal-Itriago, A Hogan, A Maurel, C Formella, I Stoddart, JJ Hall, TE Lee, A Shi, B Cole, NJ Laird, AS Badrock, AP Chung, RS Morsch, M

Amyotrophic lateral sclerosis (ALS) is a form of motor neuron disease (MND) that is characterized by the progressive loss of motor neurons within the spinal cord, brainstem, and motor cortex. Altho...

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Exploration: Explore a better future with advanced science and technology.

Liu, Y Shi, B Liang, X-J

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From mouse to mouse-ear cress: Nanomaterials as vehicles in plant biotechnology.

Xia, X Shi, B Wang, L Liu, Y Zou, Y Zhou, Y Chen, Y Zheng, M Zhu, Y Duan, J Guo, S Jang, HW Miao, Y Fan, K Bai, F Tao, W Zhao, Y Yan, Q Cheng, G Liu, H Jiao, Y Liu, S Huang, Y Ling, D Kang, W Xue, X Cui, D Huang, Y Cui, Z Sun, X Qian, Z Gu, Z Han, G Yang, Z Leong, DT Wu, A Liu, G Qu, X Shen, Y Wang, Q Lowry, GV Wang, E Liang, X-J Gardea-Torresdey, J Chen, G Parak, WJ Weiss, PS Zhang, L Stenzel, MM Fan, C Bush, AI Zhang, G Grof, CPL Wang, X Galbraith, DW Tang, BZ Offler, CE Patrick, JW Song, C-P

Biological applications of nanomaterials as delivery carriers have been embedded in traditional biomedical research for decades. Despite lagging behind, recent significant breakthroughs in the use ...

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Receptor-targeting nanomaterials alleviate binge drinking-induced neurodegeneration as artificial neurotrophins.

Yang, J Wang, L Huang, L Che, X Zhang, Z Wang, C Bai, L Liu, P Zhao, Y Hu, X Shi, B Shen, Y Liang, X-J Wu, C Xue, X

The distinguished properties of nanomaterials promote us to explore whether their intrinsic activities would be beneficial to disease treatment. Furthermore, understanding the molecular mechanism i...

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Editorial: Application for Nanotechnology for the Treatment of Brain Diseases and Disorders.

Li, J Zheng, M Zou, Y Ke, PC Zhang, M Banks, WA Shi, B

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Tuning the Elasticity of Polymersomes for Brain Tumor Targeting.

Zheng, M Du, Q Wang, X Zhou, Y Li, J Xia, X Lu, Y Yin, J Zou, Y Park, JB Shi, B

Nanoformulations show great potential for delivering drugs to treat brain tumors. However, how the mechanical properties of nanoformulations affect their ultimate brain destination is still unknown...

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Brain co-delivery of first-line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy.

Liu, Y Wang, W Zhang, D Sun, Y Li, F Zheng, M Lovejoy, DB Zou, Y Shi, B

Glioblastoma (GBM) is a central nervous system tumor with poor prognosis due to the rapid development of resistance to mono chemotherapy and poor brain targeted delivery. Chemoimmunotherapy (CIT) c...

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Near infrared-activatable biomimetic nanogels enabling deep tumor drug penetration inhibit orthotopic glioblastoma.

Zhang, D Tian, S Liu, Y Zheng, M Yang, X Zou, Y Shi, B Luo, L

Glioblastoma multiforme (GBM) is one of the most fatal malignancies due to the existence of blood-brain barrier (BBB) and the difficulty to maintain an effective drug accumulation in deep GBM lesio...

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