School of Biomedical Engineering

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Stress relaxation behavior of the transition zone in the intervertebral disc.

Vieira, L Mordechai, HS Sharabi, M Tipper, JL Tavakoli, J

The stress relaxation of the TZ region, located at the interface of the Annulus Fibrosus (AF) and Nucleus Pulposus (NP) of the disc, and how its stress is relaxed compared to the adjacent regions i...

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Aggregation-induced emission biomarkers for early detection of orthopaedic implant failure

Tavakoli, J Hu, Q Tipper, JL Tang, Y

In recent years, the substantial increase in total joint replacements for treating degenerative joint disease has heightened concerns regarding implant loosening and failure. This is especially cri...

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3D Printed Materials with Nanovoxelated Elastic Moduli.

Newman, PLH Mirkhalaf, M Gauci, SC Roohani, I Biro, M Barner-Kowollik, C Zreiqat, H

Fabrication methods that synthesize materials with higher precision and complexity at ever smaller scales are rapidly developing. Despite such advances, generating complex 3D materials with control...

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OUTCOMES OF LUMEN APPOSING METAL STENT PLACEMENT IN PATIENTS WITH SURGICALLY ALTERED ANATOMY: A MULTICENTER INTERNATIONAL EXPERIENCE

Mangiavillano, B Ramai, D Gentile, C Samanta, J Bronswijk, M Van der Merwe, S Kouanda, A Hyun, J Sun-Chuan, D Deprez, P Vargas-Madrigal, J Forti, E Mutignani, M Vanella, G Leone, R Arcidiacono, PG Robles-Medranda, C Alcivar-Vasquez, J Arevalo-Mora, M Fugazza, A Ko, C Lisotti, A Larghi, A Rizzatti, G Galasso, D Di Matteo, FM Stigliano, S Pham, KD Fusaroli, P Di Mitri, R Amata, M Crino, SF Ofosu, A Binda, C Fabbri, C Morris, JD Auriemma, F Paduano, D Calabrese, F Hassan, C Repici, A Facciorusso, A

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Integrating Cu/CuxO ternary nanocomposites with multi-walled carbon nanotubes enabling a high-performance nonenzymatic amperometric glucose sensor

Xi, W Zhang, Y Zhang, Z Chen, Y Huang, X Mou, H Deng, Z Li, Z Xu, X Zheng, W

We developed a new nonenzymatic amperometric glucose sensor by integrating a ternary nanocomposite, Cu/Cu2O/CuO (Cu/CuxO), with multi-wall carbon nanotubes (Cu/CuxO@MWCNTs) as the electrocatalyst. ...

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Bioinspired Nanoscale 3D Printing of Calcium Phosphates Using Bone Prenucleation Clusters.

Roohani, I Wang, S Xu, C Newman, P Entezari, A Lai, Y Zreiqat, H

Calcium phosphates (CaPs) are ubiquitous in biological structures, such as vertebrate bones and teeth, and have been widely used in biomedical applications. However, fabricating CaPs at the nanosca...

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Engineered nanoparticles potentials in male reproduction.

Zhao, F Fan, M Jing, Z Zhang, Y Wang, Y Zhou, C Liu, Y Aitken, RJ Xia, X

BACKGROUND: The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work-r...

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Ketogenic therapy towards precision medicine for brain diseases.

Liu, Y Fan, L Yang, H Wang, D Liu, R Shan, T Xia, X

Precision nutrition and nutrigenomics are emerging in the development of therapies for multiple diseases. The ketogenic diet (KD) is the most widely used clinical diet, providing high fat, low carb...

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P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker.

Yuan, Z Jing, H Deng, Y Liu, M Jiang, T Jin, X Lin, W Liu, Y Yin, J

Glioblastoma stem cells (GSCs) are pivotal in the recurrence and drug resistance of glioblastoma multiforme (GBM). However, precision therapeutic and diagnostic markers for GSCs have not been fully...

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Engineering Nanomedicine for Non-Viral RNA-Based Gene Therapy of Glioblastoma.

He, W Wang, N Wang, Y Liu, M Qing, Q Su, Q Zou, Y Liu, Y

Glioblastoma multiforme (GBM) is the most common type of malignant tumor of the central nervous system, characterized by aggressiveness, genetic instability, heterogenesis, and unpredictable clinic...

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