Advances in microfluidics in combating infectious diseases.

Tay, A; Pavesi, A; Yazdi, SR; Lim, CT; Warkiani, ME

Advances in microfluidics in combating infectious diseases.

Tay, A Pavesi, A Yazdi, SR Lim, CT Warkiani, ME

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Publisher:: PERGAMON-ELSEVIER SCIENCE LTD
Publication Type:: Journal Article
Citation:: Biotechnol Adv, 2016, 34, (4), pp. 404-421
Issue Date:: 2016-07

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Field	Value	Language
dc.contributor.author	Tay, A
dc.contributor.author	Pavesi, A
dc.contributor.author	Yazdi, SR
dc.contributor.author	Lim, CT
dc.contributor.author	Warkiani, ME
dc.date.accessioned	2022-07-12T22:53:00Z
dc.date.available	2016-02-04
dc.date.available	2022-07-12T22:53:00Z
dc.date.issued	2016-07
dc.identifier.citation	Biotechnol Adv, 2016, 34, (4), pp. 404-421
dc.identifier.issn	0734-9750
dc.identifier.issn	1873-1899
dc.identifier.uri	http://hdl.handle.net/10453/158815
dc.description.abstract	One of the important pursuits in science and engineering research today is to develop low-cost and user-friendly technologies to improve the health of people. Over the past decade, research efforts in microfluidics have been made to develop methods that can facilitate low-cost diagnosis of infectious diseases, especially in resource-poor settings. Here, we provide an overview of the recent advances in microfluidic devices for point-of-care (POC) diagnostics for infectious diseases and emphasis is placed on malaria, sepsis and AIDS/HIV. Other infectious diseases such as SARS, tuberculosis, and dengue are also briefly discussed. These infectious diseases are chosen as they contribute the most to disability-adjusted life-years (DALYs) lost according to the World Health Organization (WHO). The current state of research in this area is evaluated and projection toward future applications and accompanying challenges are also discussed.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	PERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartof	Biotechnol Adv
dc.relation.isbasedon	10.1016/j.biotechadv.2016.02.002
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	06 Biological Sciences, 09 Engineering, 10 Technology
dc.subject.classification	Biotechnology
dc.subject.mesh	Animals
dc.subject.mesh	Communicable Diseases
dc.subject.mesh	Humans
dc.subject.mesh	Mice
dc.subject.mesh	Microbiological Techniques
dc.subject.mesh	Microfluidic Analytical Techniques
dc.subject.mesh	Animals
dc.subject.mesh	Humans
dc.subject.mesh	Mice
dc.subject.mesh	Communicable Diseases
dc.subject.mesh	Microfluidic Analytical Techniques
dc.subject.mesh	Microbiological Techniques
dc.title	Advances in microfluidics in combating infectious diseases.
dc.type	Journal Article
utslib.citation.volume	34
utslib.location.activity	England
utslib.for	06 Biological Sciences
utslib.for	09 Engineering
utslib.for	10 Technology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
pubs.organisational-group	/University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	closed_access	*
dc.date.updated	2022-07-12T22:52:55Z
pubs.issue	4
pubs.publication-status	Published
pubs.volume	34
utslib.citation.issue	4

Abstract:

One of the important pursuits in science and engineering research today is to develop low-cost and user-friendly technologies to improve the health of people. Over the past decade, research efforts in microfluidics have been made to develop methods that can facilitate low-cost diagnosis of infectious diseases, especially in resource-poor settings. Here, we provide an overview of the recent advances in microfluidic devices for point-of-care (POC) diagnostics for infectious diseases and emphasis is placed on malaria, sepsis and AIDS/HIV. Other infectious diseases such as SARS, tuberculosis, and dengue are also briefly discussed. These infectious diseases are chosen as they contribute the most to disability-adjusted life-years (DALYs) lost according to the World Health Organization (WHO). The current state of research in this area is evaluated and projection toward future applications and accompanying challenges are also discussed.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/158815