Adhesion and Scratch Testing of Antibiotic Loaded Poly-Lactic Acid Biocomposite Thin Films on Metallic Implants

Karacan, I; Chou, J; Ben-Nissan, B; Macha, IJ; Juritza, A; Wang, AH; Muller, WH; Grossin, D; Taraschi, V; Oktar, FN; Swain, M

Adhesion and Scratch Testing of Antibiotic Loaded Poly-Lactic Acid Biocomposite Thin Films on Metallic Implants

Karacan, I Chou, J

Ben-Nissan, B Macha, IJ Juritza, A Wang, AH Muller, WH Grossin, D Taraschi, V Oktar, FN Swain, M

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Publisher:: Trans Tech Publications, Ltd.
Publication Type:: Journal Article
Citation:: Key Engineering Materials, 2018, 782 KEM, pp. 195-200
Issue Date:: 2018-01-01

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Field	Value	Language
dc.contributor.author	Karacan, I
dc.contributor.author	Chou, J https://orcid.org/0000-0002-7472-8016
dc.contributor.author	Ben-Nissan, B
dc.contributor.author	Macha, IJ
dc.contributor.author	Juritza, A
dc.contributor.author	Wang, AH
dc.contributor.author	Muller, WH
dc.contributor.author	Grossin, D
dc.contributor.author	Taraschi, V
dc.contributor.author	Oktar, FN
dc.contributor.author	Swain, M
dc.date.accessioned	2022-08-22T21:51:44Z
dc.date.available	2022-08-22T21:51:44Z
dc.date.issued	2018-01-01
dc.identifier.citation	Key Engineering Materials, 2018, 782 KEM, pp. 195-200
dc.identifier.issn	1013-9826
dc.identifier.issn	1662-9795
dc.identifier.uri	http://hdl.handle.net/10453/160700
dc.description.abstract	Surface modifications have been progressively applied in order to improve the mechanical, biological and chemical properties of metallic dental and orthopedic implants. Therefore, the novel and multifunctional biocomposites coating matrices, which also consist of local and targeted drug delivery systems, are the most recent applications in the medical field. In this study, gentamicin antibiotic containing HAp bioceramics were utilized in a biodegradable poly-lactic acid thin film matrix which was applied to Ti6Al4V metallic implant surfaces. Nano-indentation and scratch test methods were applied. It was observed that, bonding between coating and the substrate is strong enough to be used in implant applications. Additionally, it was observed that the hardness and young modulus values of uncoated Ti6Al4V disc which were 4.3 and 125.2 GPa, respectively. However, under the same testing conditions, it was also observed that the H values (0.6-0.8GPa) and the E (50-60 GPa) values of PLA-HAp biocomposite coated samples are slightly higher than the H values (0.4-0.6 GPa) and the E values (40-50 GPa) of only PLA coated sample.
dc.language	en
dc.publisher	Trans Tech Publications, Ltd.
dc.relation.ispartof	Key Engineering Materials
dc.relation.isbasedon	10.4028/www.scientific.net/KEM.782.195
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	09 Engineering
dc.subject.classification	Materials
dc.title	Adhesion and Scratch Testing of Antibiotic Loaded Poly-Lactic Acid Biocomposite Thin Films on Metallic Implants
dc.type	Journal Article
utslib.citation.volume	782 KEM
utslib.for	09 Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	closed_access	*
dc.date.updated	2022-08-22T21:51:43Z
pubs.publication-status	Published
pubs.volume	782 KEM

Abstract:

Surface modifications have been progressively applied in order to improve the mechanical, biological and chemical properties of metallic dental and orthopedic implants. Therefore, the novel and multifunctional biocomposites coating matrices, which also consist of local and targeted drug delivery systems, are the most recent applications in the medical field. In this study, gentamicin antibiotic containing HAp bioceramics were utilized in a biodegradable poly-lactic acid thin film matrix which was applied to Ti6Al4V metallic implant surfaces. Nano-indentation and scratch test methods were applied. It was observed that, bonding between coating and the substrate is strong enough to be used in implant applications. Additionally, it was observed that the hardness and young modulus values of uncoated Ti6Al4V disc which were 4.3 and 125.2 GPa, respectively. However, under the same testing conditions, it was also observed that the H values (0.6-0.8GPa) and the E (50-60 GPa) values of PLA-HAp biocomposite coated samples are slightly higher than the H values (0.4-0.6 GPa) and the E values (40-50 GPa) of only PLA coated sample.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/160700